ID   Y1998_MYCLE             Reviewed;         659 AA.
AC   P53525;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Uncharacterized protein ML1998;
GN   OrderedLocusNames=ML1998; ORFNames=o659;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7476188; DOI=10.1111/j.1365-2958.1995.tb02317.x;
RA   Fsihi H., Cole S.T.;
RT   "The Mycobacterium leprae genome: systematic sequence analysis identifies
RT   key catabolic enzymes, ATP-dependent transport systems and a novel polA
RT   locus associated with genomic variability.";
RL   Mol. Microbiol. 16:909-919(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.tuberculosis Rv0102. {ECO:0000305}.
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DR   EMBL; Z46257; CAA86362.1; -; Genomic_DNA.
DR   EMBL; AL583924; CAC30953.1; -; Genomic_DNA.
DR   PIR; S77658; S77658.
DR   RefSeq; NP_302349.1; NC_002677.1.
DR   RefSeq; WP_010908669.1; NC_002677.1.
DR   AlphaFoldDB; P53525; -.
DR   STRING; 272631.ML1998; -.
DR   EnsemblBacteria; CAC30953; CAC30953; CAC30953.
DR   KEGG; mle:ML1998; -.
DR   PATRIC; fig|272631.5.peg.3758; -.
DR   Leproma; ML1998; -.
DR   eggNOG; COG3336; Bacteria.
DR   HOGENOM; CLU_016803_0_0_11; -.
DR   OMA; YVVYFTP; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019108; Caa3_assmbl_CtaG-rel.
DR   InterPro; IPR008457; Cu-R_CopD.
DR   Pfam; PF09678; Caa3_CtaG; 1.
DR   Pfam; PF05425; CopD; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..659
FT                   /note="Uncharacterized protein ML1998"
FT                   /id="PRO_0000103674"
FT   TRANSMEM        24..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        115..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        242..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        279..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        311..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        365..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        393..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        433..453
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        490..510
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        517..537
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        550..570
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        596..616
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   659 AA;  71246 MW;  2C1D90C6BF720E39 CRC64;
     MQTDEPTGTA TSAIRIPPLI SLRTTLMVAG LLGNVVAVAA YGLFSRTERY GAVGNPDPGS
     FIGVAEPVGY FGASLSSALC LGALIYFVMM VWPQADGLID AQAFRIHLAE ERVSIGWLAF
     ALTMVVVQAA NDSGVTPAEL RTGAALFNAI TTSETSRAWI VVTICALLVT LTLRVIIRYS
     DHFVLLIPAV IGVIATAVTG NAGQGPDHDY ATSAVIVFAL AIAALSGLKI TAALTEVTPS
     RAVLIVQVVC GVLALAYGAE LVYLLSPGAA MIDSDFGRLG LVAGVLVTLV CFSDCWALVM
     GRPHSDHRTR LTALAMMAVT AATAAMSVQT APRFLTHRFT AWDVFLGYEL PQPPNIVRFF
     TVWRFDSLIG ATAIVLGIGY VAGFVRVRRA GNTWPVGRLV AWLTGCVALV FTSSSGVRTY
     GSAMFSVHMA EHMTLNMFIP VLLVLGGPVT LALRALSAAG DGQQPGPREW LTWLMHSSVT
     AFLSHPVTNF ILFVGSPYIV YFTPLFDTLV RYHWGHEFMA IHFLLVGYIF YWAIIGIDPG
     PRRLPYLARI GLLFAVMPFH AFFGIALMTM TSAISAEFYR SVNLPWLASI DADQHIGGAI
     AWSATELPVI IVIVALMAQW ARQDHRVAVR EDRHADSTYA DDDLNAYNAM LRELSRMRR