ID   Y1998_MYCTO             Reviewed;         258 AA.
AC   P9WLN8; L0TB19; Q10859;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Uncharacterized protein MT2054;
GN   OrderedLocusNames=MT2054;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
RN   [2]
RP   INDUCTION BY NITRIC OXIDE (NO) AND BY HYPOXIA, AND DORMANCY REGULON.
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12953092; DOI=10.1084/jem.20030205;
RA   Voskuil M.I., Schnappinger D., Visconti K.C., Harrell M.I., Dolganov G.M.,
RA   Sherman D.R., Schoolnik G.K.;
RT   "Inhibition of respiration by nitric oxide induces a Mycobacterium
RT   tuberculosis dormancy program.";
RL   J. Exp. Med. 198:705-713(2003).
CC   -!- INDUCTION: A member of the dormancy regulon. Induced in response to
CC       reduced oxygen tension (hypoxia) and low levels of nitric oxide (NO).
CC       {ECO:0000269|PubMed:12953092}.
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DR   EMBL; AE000516; AAK46331.1; -; Genomic_DNA.
DR   PIR; D70758; D70758.
DR   RefSeq; WP_003899122.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WLN8; -.
DR   SMR; P9WLN8; -.
DR   EnsemblBacteria; AAK46331; AAK46331; MT2054.
DR   KEGG; mtc:MT2054; -.
DR   PATRIC; fig|83331.31.peg.2211; -.
DR   HOGENOM; CLU_027389_2_3_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd00377; ICL_PEPM; 1.
DR   Gene3D; 3.20.20.60; -; 1.
DR   InterPro; IPR039556; ICL/PEPM.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR   SUPFAM; SSF51621; SSF51621; 1.
PE   2: Evidence at transcript level;
FT   CHAIN           1..258
FT                   /note="Uncharacterized protein MT2054"
FT                   /id="PRO_0000427446"
SQ   SEQUENCE   258 AA;  27253 MW;  BA89B3FDB51D9E5E CRC64;
     MSFHDLHHQG VPFVLPNAWD VPSALAYLAE GFTAIGTTSF GVSSSGGHPD GHRATRGANI
     ALAAALAPLQ CYVSVDIEDG YSDEPDAIAD YVAQLSTAGI NIEDSSAEKL IDPALAAAKI
     VAIKQRNPEV FVNARVDTYW LRQHADTTST IQRALRYVDA GADGVFVPLA NDPDELAELT
     RNIPCPVNTL PVPGLTIADL GELGVARVST GSVPYSAGLY AAAHAARAVS DGEQLPRSVP
     YAELQARLVD YENRTSTT