Y1999_MYCTO
ID Y1999_MYCTO Reviewed; 440 AA.
AC P9WQM2; L0T9W4; P63349; Q10858;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 33.
DE RecName: Full=Uncharacterized transporter MT2055;
GN OrderedLocusNames=MT2055;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- FUNCTION: Probable amino-acid or metabolite transport protein.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. {ECO:0000305}.
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DR EMBL; AE000516; AAK46332.1; -; Genomic_DNA.
DR PIR; E70758; E70758.
DR RefSeq; WP_003410039.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WQM2; -.
DR SMR; P9WQM2; -.
DR EnsemblBacteria; AAK46332; AAK46332; MT2055.
DR KEGG; mtc:MT2055; -.
DR PATRIC; fig|83331.31.peg.2212; -.
DR HOGENOM; CLU_007946_15_12_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002293; AA/rel_permease1.
DR Pfam; PF13520; AA_permease_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..440
FT /note="Uncharacterized transporter MT2055"
FT /id="PRO_0000426751"
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 117..137
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 155..175
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 183..203
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 229..249
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 346..366
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 400..420
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 440 AA; 45267 MW; 9592EE0A842D18CD CRC64;
MRRPLDPRDI PDELRRRLGL LDAVVIGLGS MIGAGIFAAL APAAYAAGSG LLLGLAVAAV
VAYCNAISSA RLAARYPASG GTYVYGRMRL GDFWGYLAGW GFVVGKTASC AAMALTVGFY
VWPAQAHAVA VAVVVALTAV NYAGIQKSAW LTRSIVAVVL VVLTAVVVAA YGSGAADPAR
LDIGVDAHVW GMLQAAGLLF FAFAGYARIA TLGEEVRDPA RTIPRAIPLA LGITLAVYAL
VAVAVIAVLG PQRLARAAAP LSEAMRVAGV NWLIPVVQIG AAVAALGSLL ALILGVSRTT
LAMARDRHLP RWLAAVHPRF KVPFRAELVV GAVVAALAAT ADIRGAIGFS SFGVLVYYAI
ANASALTLGL DEGRPRRLIP LVGLIGCVVL AFALPLSSVA AGAAVLGVGV AAYGVRRIIT
RRARQTDSGD TQRSGHPSAT