ID   Y199_DEIRA              Reviewed;          96 AA.
AC   Q9RXV7; Q9ZNA1;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=Nucleoid-associated protein DR_0199 {ECO:0000255|HAMAP-Rule:MF_00274};
GN   OrderedLocusNames=DR_0199;
OS   Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG
OS   4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422).
OC   Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae;
OC   Deinococcus.
OX   NCBI_TaxID=243230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB
RC   9279 / R1 / VKM B-1422;
RA   Kitayama S., Narumi I., Kikuchi M., Watanabe H.;
RT   "Repair of interstrand cross-links in DNA and recR mutation of Deinococcus
RT   radiodurans.";
RL   Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB
RC   9279 / R1 / VKM B-1422;
RX   PubMed=10567266; DOI=10.1126/science.286.5444.1571;
RA   White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D.,
RA   Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L.,
RA   Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M.,
RA   Vamathevan J.J., Lam P., McDonald L.A., Utterback T.R., Zalewski C.,
RA   Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D.,
RA   Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C.,
RA   Fraser C.M.;
RT   "Genome sequence of the radioresistant bacterium Deinococcus radiodurans
RT   R1.";
RL   Science 286:1571-1577(1999).
RN   [3]
RP   FUNCTION, DNA-BINDING, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB
RC   9279 / R1 / VKM B-1422;
RX   PubMed=22282513; DOI=10.1099/mic.0.053702-0;
RA   Wang H., Wang F., Hua X., Ma T., Chen J., Xu X., Wang L., Tian B., Hua Y.;
RT   "Genetic and biochemical characteristics of the histone-like protein DR0199
RT   in Deinococcus radiodurans.";
RL   Microbiology 158:936-943(2012).
CC   -!- FUNCTION: Binds to DNA and alters its conformation. May be involved in
CC       regulation of gene expression, nucleoid organization and DNA
CC       protection. {ECO:0000255|HAMAP-Rule:MF_00274,
CC       ECO:0000269|PubMed:22282513}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00274}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_00274, ECO:0000269|PubMed:22282513}.
CC   -!- DISRUPTION PHENOTYPE: Mutants display an increased sensitivity to
CC       oxidative stress, and a slightly increased sensitivity to ionizing
CC       radiation and UV exposure. {ECO:0000269|PubMed:22282513}.
CC   -!- SIMILARITY: Belongs to the YbaB/EbfC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00274}.
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DR   EMBL; AB020241; BAA34649.1; -; Genomic_DNA.
DR   EMBL; AE000513; AAF09786.1; -; Genomic_DNA.
DR   PIR; A75548; A75548.
DR   RefSeq; NP_293923.1; NC_001263.1.
DR   RefSeq; WP_010886845.1; NZ_CP015081.1.
DR   AlphaFoldDB; Q9RXV7; -.
DR   SMR; Q9RXV7; -.
DR   STRING; 243230.DR_0199; -.
DR   EnsemblBacteria; AAF09786; AAF09786; DR_0199.
DR   KEGG; dra:DR_0199; -.
DR   PATRIC; fig|243230.17.peg.363; -.
DR   eggNOG; COG0718; Bacteria.
DR   HOGENOM; CLU_140930_2_2_0; -.
DR   InParanoid; Q9RXV7; -.
DR   OMA; MGNMMKQ; -.
DR   OrthoDB; 1883809at2; -.
DR   Proteomes; UP000002524; Chromosome I.
DR   GO; GO:0043590; C:bacterial nucleoid; IEA:UniProtKB-UniRule.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   Gene3D; 3.30.1310.10; -; 1.
DR   HAMAP; MF_00274; DNA_YbaB_EbfC; 1.
DR   InterPro; IPR036894; YbaB-like_sf.
DR   InterPro; IPR004401; YbaB/EbfC.
DR   PANTHER; PTHR33449; PTHR33449; 1.
DR   Pfam; PF02575; YbaB_DNA_bd; 1.
DR   PIRSF; PIRSF004555; UCP004555; 1.
DR   SUPFAM; SSF82607; SSF82607; 1.
DR   TIGRFAMs; TIGR00103; DNA_YbaB_EbfC; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; DNA-binding; Reference proteome.
FT   CHAIN           1..96
FT                   /note="Nucleoid-associated protein DR_0199"
FT                   /id="PRO_0000170390"
FT   CONFLICT        88..96
FT                   /note="TAGLGLPGF -> RRAWDCPAFECDRAGAWSSEGQTV (in Ref. 1;
FT                   BAA34649)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   96 AA;  10006 MW;  18342F2EDCCDA76A CRC64;
     MDMKKLMKQM QQAQVAAGKI QDELAAQSVE GTASGLVTVQ MNGHGKVTSL KIKPEAVDGD
     DVEALEDLIL AAINDAAEKA EGLQREATAG LGLPGF