ID   Y2001_MYCBO             Reviewed;         481 AA.
AC   Q7TZ67; A0A1R3XZV9; X2BJP4;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Uncharacterized transporter Mb2001c;
GN   OrderedLocusNames=BQ2027_MB2001C;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- FUNCTION: Probable amino-acid or metabolite transport protein.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC       superfamily. {ECO:0000305}.
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DR   EMBL; LT708304; SIU00606.1; -; Genomic_DNA.
DR   RefSeq; NP_855651.1; NC_002945.3.
DR   RefSeq; WP_003409946.1; NC_002945.4.
DR   AlphaFoldDB; Q7TZ67; -.
DR   SMR; Q7TZ67; -.
DR   EnsemblBacteria; SIU00606; SIU00606; BQ2027_MB2001C.
DR   PATRIC; fig|233413.5.peg.2197; -.
DR   OMA; KPFWPSC; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR002293; AA/rel_permease1.
DR   Pfam; PF13520; AA_permease_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..481
FT                   /note="Uncharacterized transporter Mb2001c"
FT                   /id="PRO_0000054224"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        167..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        258..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        303..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        377..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        411..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        446..466
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   481 AA;  51058 MW;  41F1B25EC1E3A51F CRC64;
     MVGPRTRGYA IHKLGFCSVV MLGINSIIGA GIFLTPGEVI GLAGPFAPMA YVLAGIFAGV
     VAIVFATAAR YVRTNGASYA YTTAAFGRRI GIYVGVTHAI TASIAWGVLA SFFVSTLLRV
     AFPDKAWADA EQLFSVKTLT FLGFIGVLLA INLFGNRAIK WANGTSTVGK AFALSAFIVG
     GLWIITTQHV NNYATAWSAY SATPYSLLGV AEIGKGTFSS MALATIVALY AFTGFESIAN
     AAEEMDAPDR NLPRAIPIAI FSVGAIYLLT LTVAMLLGSN KIAASGDTVK LAAAIGNATF
     RTIIVVGALI SMFGINVAAS FGAPRLWTAL ADSGVLPTRL SRKNQYDVPM VSFAITASLA
     LAFPLALRFD NLHLTGLAVI ARFVQFIIVP IALIALARSQ AVEHAAVRRN AFTDKVLPLV
     AIVVSVGLAV SYDYRCIFLV RGGPNYFSIA LIVITFIVVP AMAYLHYYRI IRRVGDRPST
     R