ID   Y2004_STAAR             Reviewed;         200 AA.
AC   Q6GFE5;
DT   21-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=UPF0316 protein SAR2004 {ECO:0000255|HAMAP-Rule:MF_01515};
GN   OrderedLocusNames=SAR2004;
OS   Staphylococcus aureus (strain MRSA252).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282458;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MRSA252;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01515};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01515}.
CC   -!- SIMILARITY: Belongs to the UPF0316 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01515}.
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DR   EMBL; BX571856; CAG40989.1; -; Genomic_DNA.
DR   RefSeq; WP_000011542.1; NC_002952.2.
DR   AlphaFoldDB; Q6GFE5; -.
DR   SMR; Q6GFE5; -.
DR   KEGG; sar:SAR2004; -.
DR   HOGENOM; CLU_106166_1_0_9; -.
DR   OMA; KLALGYI; -.
DR   OrthoDB; 1480783at2; -.
DR   Proteomes; UP000000596; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01515; UPF0316; 1.
DR   InterPro; IPR019264; DUF2179.
DR   InterPro; IPR044035; DUF5698.
DR   InterPro; IPR022930; UPF0316.
DR   PANTHER; PTHR40060; PTHR40060; 1.
DR   Pfam; PF10035; DUF2179; 1.
DR   Pfam; PF18955; DUF5698; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..200
FT                   /note="UPF0316 protein SAR2004"
FT                   /id="PRO_0000171953"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01515"
FT   TRANSMEM        40..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01515"
FT   TRANSMEM        66..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01515"
SQ   SEQUENCE   200 AA;  22955 MW;  5640A6B01EC520AF CRC64;
     MSFVTENPWL MVLTIFIINV CYVTFLTMRT ILTLKGYRYI AASVSFLEVL VYIVGLGLVM
     SNLDHIQNII AYAFGFSIGI IVGMKIEEKL ALGYTVVNVT SAEYELDLPN ELRNLGYGVT
     HYAAFGRDGS RMVMQILTPR KYERKLMDTI KNLDPKAFII AYEPRNIHGG FWTKGIRRRK
     LKDYEPEELE SVVEHEIQSK