ID   Y200_PYRAB              Reviewed;         202 AA.
AC   Q9V274; G8ZG35;
DT   14-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=UPF0056 membrane protein PYRAB02000;
GN   OrderedLocusNames=PYRAB02000; ORFNames=PAB2220;
OS   Pyrococcus abyssi (strain GE5 / Orsay).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=272844;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GE5 / Orsay;
RX   PubMed=12622808; DOI=10.1046/j.1365-2958.2003.03381.x;
RA   Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O.,
RA   Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J.,
RA   Weissenbach J., Zivanovic Y., Forterre P.;
RT   "An integrated analysis of the genome of the hyperthermophilic archaeon
RT   Pyrococcus abyssi.";
RL   Mol. Microbiol. 47:1495-1512(2003).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=GE5 / Orsay;
RX   PubMed=22057919; DOI=10.1007/s00284-011-0035-x;
RA   Gao J., Wang J.;
RT   "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and
RT   Pyrococcus furiosus DSM 3638.";
RL   Curr. Microbiol. 64:118-129(2012).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0056 (MarC) family. {ECO:0000305}.
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DR   EMBL; AJ248283; CAB49124.1; -; Genomic_DNA.
DR   EMBL; HE613800; CCE69576.1; -; Genomic_DNA.
DR   PIR; E75209; E75209.
DR   RefSeq; WP_010867324.1; NC_000868.1.
DR   AlphaFoldDB; Q9V274; -.
DR   EnsemblBacteria; CAB49124; CAB49124; PAB2220.
DR   GeneID; 1495087; -.
DR   KEGG; pab:PAB2220; -.
DR   PATRIC; fig|272844.11.peg.214; -.
DR   eggNOG; arCOG01997; Archaea.
DR   HOGENOM; CLU_079909_1_0_2; -.
DR   OMA; IRMIFPQ; -.
DR   OrthoDB; 99403at2157; -.
DR   PhylomeDB; Q9V274; -.
DR   Proteomes; UP000000810; Chromosome.
DR   Proteomes; UP000009139; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002771; Multi_antbiot-R_MarC.
DR   PANTHER; PTHR33508; PTHR33508; 1.
DR   Pfam; PF01914; MarC; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..202
FT                   /note="UPF0056 membrane protein PYRAB02000"
FT                   /id="PRO_0000156919"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        174..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   202 AA;  21436 MW;  AAF0F1B24EB82461 CRC64;
     MLQEILSSAL LMLIMIDPSD KILLVSLLRE DFHIEDVKSL IIRANIIGFL LLLIFAVAGK
     IILQDIFHIE LDALRVAGGF VLFKIGLEAL ESGGMVTIKK EKNILALAAV PVATPLIAGP
     AAITAAITLT AEYGIVVSVT ATFIAIVITA VLMLLSLYLM RGINKTALSV TIRIIGLFIM
     AIGAQMMISG AGGIVLSILK EA