ID   Y2016_DICDI             Reviewed;         918 AA.
AC   Q54DV3;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=von Willebrand factor A domain-containing protein DDB_G0292016;
GN   ORFNames=DDB_G0292016;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000187; EAL61364.1; -; Genomic_DNA.
DR   RefSeq; XP_629769.1; XM_629767.1.
DR   AlphaFoldDB; Q54DV3; -.
DR   SMR; Q54DV3; -.
DR   PaxDb; Q54DV3; -.
DR   EnsemblProtists; EAL61364; EAL61364; DDB_G0292016.
DR   GeneID; 8628445; -.
DR   KEGG; ddi:DDB_G0292016; -.
DR   dictyBase; DDB_G0292016; -.
DR   eggNOG; ENOG502QRPK; Eukaryota.
DR   HOGENOM; CLU_327738_0_0_1; -.
DR   InParanoid; Q54DV3; -.
DR   OMA; HPIHQDF; -.
DR   PhylomeDB; Q54DV3; -.
DR   PRO; PR:Q54DV3; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   Gene3D; 3.40.50.410; -; 1.
DR   InterPro; IPR013694; VIT.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF08487; VIT; 1.
DR   Pfam; PF13768; VWA_3; 1.
DR   SMART; SM00609; VIT; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS51468; VIT; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..918
FT                   /note="von Willebrand factor A domain-containing protein
FT                   DDB_G0292016"
FT                   /id="PRO_0000389207"
FT   DOMAIN          44..172
FT                   /note="VIT"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00801"
FT   DOMAIN          299..467
FT                   /note="VWFA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00219"
FT   REGION          625..814
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        649..691
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        721..743
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        744..773
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        782..814
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   918 AA;  102342 MW;  9FE067C2DF55B7EF CRC64;
     MFSSITSKLS AISGGSSKND YKEANYYNYF RILEKKQTEE IARKRCGLYS LKNHNNVFVL
     KEFSIETEIN DCSSTSIWTQ SYSNDSNTPV EAKYQLPLHP TSVVSNFQIE YQGKVIQGKI
     KEKEKALEKY NDAIASGGQA FMATKSDDGY FNLTLGNLPP KENVKVRVVI SSELGTHTDG
     QLHYCLHRYM FPSYAFNFNY NVVLKFSIPI KSIDCDGFDV NVNYKENSSK KEAKITSKSQ
     HTSGVKKNII LIIQPVELNE PKSMIEYIGG GDDKSYATAI NFYPSFKNVN PDEVYQKSEF
     IFLIDCSGSM SGQSINKARR AMEIIIRSLN EQHKVNIYCF GSSFNKVFDK SRVYNDETLE
     IAGSFVEKIS ANLGGTELLP PMVDILSSPN DPEYPRQVFI LTDGEISERD KLIDYVAKEA
     NTTRIFTYGI GASVDQELVI GLSKACKGYY EMIKETTNME KQVMKLLNVA FEPMLSNIKL
     DWSSCGLVDV IQAPSHIRPL FNQERMMIYS MIPSNQTNQD IINASIETSK PLIITLTGDG
     PKGNVLSFPI TLDFKNDLST NSNQIHTLAA FKHIQDLEES ERKEKKDNKD KIVELGKKYG
     LVSKHTSYIV TADSDNVTEE TMKTVDIMNQ SPPIRPGGRI VSRGGGRSGA SGALSSSILS
     RKRSSSPSTA TKRSSSSSFS SSYLSLSSSS QKKKKEVSRS DDDDDDEKIE NCVESYESDG
     GDQSSEQDEE EEDDCDDFHE DLDEDLGATA MDVDKKECEK ECKKKDSSKV DLKVKPSKVP
     LPSRSPSVSK PTTTSLLSPS PKSAPSAPSQ QKSVKSTGDL LIDLLKIQKS NGSWTKSSID
     QLKIPTDKAP AELSTTELND IWVTIIVIAK IVKFFSSEKA QYELAIQKST RWVKLQLSKL
     NLPENTFDKF LSNAKSLV