Y2022_MYCBO
ID Y2022_MYCBO Reviewed; 440 AA.
AC P63350; A0A1R3Y010; Q10858; X2BJI4;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=Uncharacterized transporter Mb2022c;
GN OrderedLocusNames=BQ2027_MB2022C;
OS Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=233413;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT "The complete genome sequence of Mycobacterium bovis.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA Robbe-Austerman S., Gordon S.V.;
RT "Updated reference genome sequence and annotation of Mycobacterium bovis
RT AF2122/97.";
RL Genome Announc. 5:E00157-E00157(2017).
CC -!- FUNCTION: Probable amino-acid or metabolite transport protein.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. {ECO:0000305}.
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DR EMBL; LT708304; SIU00629.1; -; Genomic_DNA.
DR RefSeq; NP_855672.1; NC_002945.3.
DR RefSeq; WP_003410039.1; NC_002945.4.
DR AlphaFoldDB; P63350; -.
DR SMR; P63350; -.
DR PRIDE; P63350; -.
DR EnsemblBacteria; SIU00629; SIU00629; BQ2027_MB2022C.
DR PATRIC; fig|233413.5.peg.2221; -.
DR OMA; RDRHLPH; -.
DR Proteomes; UP000001419; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002293; AA/rel_permease1.
DR Pfam; PF13520; AA_permease_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..440
FT /note="Uncharacterized transporter Mb2022c"
FT /id="PRO_0000054226"
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 117..137
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 155..175
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 183..203
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 229..249
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 346..366
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 400..420
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 440 AA; 45267 MW; 9592EE0A842D18CD CRC64;
MRRPLDPRDI PDELRRRLGL LDAVVIGLGS MIGAGIFAAL APAAYAAGSG LLLGLAVAAV
VAYCNAISSA RLAARYPASG GTYVYGRMRL GDFWGYLAGW GFVVGKTASC AAMALTVGFY
VWPAQAHAVA VAVVVALTAV NYAGIQKSAW LTRSIVAVVL VVLTAVVVAA YGSGAADPAR
LDIGVDAHVW GMLQAAGLLF FAFAGYARIA TLGEEVRDPA RTIPRAIPLA LGITLAVYAL
VAVAVIAVLG PQRLARAAAP LSEAMRVAGV NWLIPVVQIG AAVAALGSLL ALILGVSRTT
LAMARDRHLP RWLAAVHPRF KVPFRAELVV GAVVAALAAT ADIRGAIGFS SFGVLVYYAI
ANASALTLGL DEGRPRRLIP LVGLIGCVVL AFALPLSSVA AGAAVLGVGV AAYGVRRIIT
RRARQTDSGD TQRSGHPSAT
