ID   Y2026_MYCTO             Reviewed;         294 AA.
AC   P9WFD0; L0TBA6; O53472; Q7D7L7;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 35.
DE   RecName: Full=Universal stress protein MT2085;
GN   OrderedLocusNames=MT2085;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SIMILARITY: Belongs to the universal stress protein A family.
CC       {ECO:0000305}.
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DR   EMBL; AE000516; AAK46364.1; -; Genomic_DNA.
DR   PIR; A70942; A70942.
DR   RefSeq; WP_003410150.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WFD0; -.
DR   SMR; P9WFD0; -.
DR   EnsemblBacteria; AAK46364; AAK46364; MT2085.
DR   KEGG; mtc:MT2085; -.
DR   PATRIC; fig|83331.31.peg.2249; -.
DR   HOGENOM; CLU_049301_2_3_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.620; -; 2.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR006015; Universal_stress_UspA.
DR   InterPro; IPR006016; UspA.
DR   Pfam; PF00582; Usp; 2.
DR   PRINTS; PR01438; UNVRSLSTRESS.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding.
FT   CHAIN           1..294
FT                   /note="Universal stress protein MT2085"
FT                   /id="PRO_0000428560"
FT   BINDING         13
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P9WFD7"
FT   BINDING         117..123
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P9WFD7"
FT   BINDING         131..132
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P9WFD7"
FT   BINDING         164
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P9WFD7"
FT   BINDING         197
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P9WFD7"
FT   BINDING         261..267
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P9WFD7"
FT   BINDING         275..277
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P9WFD7"
SQ   SEQUENCE   294 AA;  31456 MW;  F0627782110F7142 CRC64;
     MSAATAKYGI LVGVDGSAQS NAAVAWAARE AVMRQLPITL LHIVAPVVVG WPVGQLYANM
     TEWQKDNAQQ VIEQAREALT NSLGESKPPQ VHTELVFSNV VPTLIDASQQ AWLMVVGSQG
     MGALGRLLLG SISTALLHHA RCPVAIIHSG NGATPDSDAP VLVGIDGSPA SEAATALAFD
     EASRRRVDLV ALHAWTDLGM FPVLGMDWRE REKREAEVLA ERLAGWQEQY PDVRVHRSLV
     CDKPARWLLE HSEQAQLVVV GSHGRGGFSG MLLGSVSSAV AHSVRIPVIV VRPS