ID   Y2027_AQUAE             Reviewed;         364 AA.
AC   O67821;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Uncharacterized protein aq_2027;
GN   OrderedLocusNames=aq_2027;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
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DR   EMBL; AE000657; AAC07788.1; -; Genomic_DNA.
DR   PIR; A70474; A70474.
DR   RefSeq; NP_214390.1; NC_000918.1.
DR   RefSeq; WP_010881326.1; NC_000918.1.
DR   AlphaFoldDB; O67821; -.
DR   SMR; O67821; -.
DR   STRING; 224324.aq_2027; -.
DR   EnsemblBacteria; AAC07788; AAC07788; aq_2027.
DR   KEGG; aae:aq_2027; -.
DR   eggNOG; COG2199; Bacteria.
DR   eggNOG; COG2206; Bacteria.
DR   HOGENOM; CLU_760001_0_0_0; -.
DR   InParanoid; O67821; -.
DR   OrthoDB; 1755994at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   Pfam; PF01966; HD; 1.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF55073; SSF55073; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS51832; HD_GYP; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..364
FT                   /note="Uncharacterized protein aq_2027"
FT                   /id="PRO_0000174397"
FT   DOMAIN          1..192
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01176"
FT   DOMAIN          231..364
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00095"
SQ   SEQUENCE   364 AA;  42016 MW;  4022756E079B7276 CRC64;
     MKLNAEFFIR LIGLRDAYTR GHTERGVFYA QLIGKELGLT SQEIELLKLG GYIHDVGKVA
     IPDVILLKPA KLTPEEYEIM KLHVELGYEM VKDLEIPWES LEVLLYHQEK YDGTGYPFGK
     KGEEIPLLAR IYTIADSFEA MTTRRIYKRA KSWNEALKEL EELAGKQFDP DIVPYAVRAL
     SRIRALPLGE NNCPLEIEKI RWSFYYLDSI TGAVKGDLFL PTLRAFIEKG EPFCLTLFDI
     YNLLEFNRKH GWEEGNRVLK KLVEAINIQC CSAVDVKDVI IKLMKQDILD LTSSVIFRIG
     GDEFAVIAPY IPPQEKVINV VRTMEEHGVK IKFFQMQFPY TFTKYEEVLE VLRNFMKKEG
     KKGI