ID   Y2028_DICDI             Reviewed;         932 AA.
AC   Q54DU5;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=von Willebrand factor A domain-containing protein DDB_G0292028;
GN   ORFNames=DDB_G0292028;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000187; EAL61370.1; -; Genomic_DNA.
DR   RefSeq; XP_629777.1; XM_629775.1.
DR   AlphaFoldDB; Q54DU5; -.
DR   SMR; Q54DU5; -.
DR   STRING; 44689.DDB0184172; -.
DR   PaxDb; Q54DU5; -.
DR   EnsemblProtists; EAL61370; EAL61370; DDB_G0292028.
DR   GeneID; 8628454; -.
DR   KEGG; ddi:DDB_G0292028; -.
DR   dictyBase; DDB_G0292028; -.
DR   eggNOG; ENOG502QRPK; Eukaryota.
DR   HOGENOM; CLU_327738_0_0_1; -.
DR   InParanoid; Q54DU5; -.
DR   OMA; QRAIMTT; -.
DR   PhylomeDB; Q54DU5; -.
DR   PRO; PR:Q54DU5; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   Gene3D; 3.40.50.410; -; 1.
DR   InterPro; IPR013694; VIT.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF08487; VIT; 1.
DR   Pfam; PF13768; VWA_3; 1.
DR   SMART; SM00609; VIT; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS51468; VIT; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..932
FT                   /note="von Willebrand factor A domain-containing protein
FT                   DDB_G0292028"
FT                   /id="PRO_0000389208"
FT   DOMAIN          95..222
FT                   /note="VIT"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00801"
FT   DOMAIN          342..521
FT                   /note="VWFA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00219"
FT   REGION          1..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          661..752
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          800..834
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..41
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        661..690
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        691..746
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   932 AA;  103712 MW;  FCFE5A28A4F49E89 CRC64;
     MNFIKKVIGG GSSKSKTDIK IEDEQHEQQH EQQHEKQQIP DKISTSKVNS PCVPPTCTYI
     SKENVRSDLS LIKDFNSAYY YNYYRTLEKN STNLLTSPGL NTKVVSNQFT LKEFNIVSEM
     TDSCIVSVWT QKYSNLSLTP VEAVYQIPLA PYATVSDFSV ILKDKVLKGK IKENEKAKEK
     YNDAIASGGQ AFLAEKVEGF FKLQIGNLPP QEDVTVNITI TSEIGTHLES LHFCLHRFIF
     PKSAFKFNYT LNASLSTPIE TIEMDHFQPT ITYKDESKTN ATVTISTENG VSNNIIAIIV
     PKYSEKPESF IEYSPIDKSY ALAINFYPKF SVGLDEVDQK SEFIFVLDCS GSMSGKPIEK
     SKMALEICMR SLNENSKFNI VCFGSNFNKL FETSKHYNDE TLQKASEYIN RIDANLGGTE
     LLEPIVDILS KESDPEFPRQ VFILTDGEIS NRDKLIDYVG KEANTTRIFT YGIGSYVDKE
     LIVGVSKACK GYYEMIVDNS DMEEKVMKLI SIAMQPTLSN IKVDWGVLSN VVQSPAQIRP
     LFNQERMMIY ATLDKEPTEK QVTVILSGNG PLSERISFPV DLDFSKANQS TSHIHTLSAF
     KHIQDLEESE RKEKKDNKDK IVKLGKRFGL VSKHTSYIVT ADSDKVTEET MKTVQVLEPT
     QQINTSPGSG SGFIPTTRVQ GSSSVFPSSP TPLSGPSPYT VCAPPPPPPT SSPYTNCAPP
     PPQFSRCIAP QPYQSAPAPP APPAPSRLSQ AQSQMDYCDQ ELLCESLEGD LLVEEEELEC
     KEIECSPPQK LSYITPFAPT SQISQSSREC RSKKSSSPTI QKSSSLPSRP STSSSSLIEI
     IRQQKANGSF TKSSVSSFIN VDTPPPSSDI PEDVWTTLLI IANFILNFDS QKSQWELVSQ
     KATKFVKQQI IKSSIASTFE TLLESAKKSI SN