ID   Y2034_CUTAK             Reviewed;         525 AA.
AC   Q6A666;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   25-MAY-2022, entry version 115.
DE   RecName: Full=Uncharacterized transporter PPA2034;
GN   OrderedLocusNames=PPA2034;
OS   Cutibacterium acnes (strain DSM 16379 / KPA171202) (Propionibacterium
OS   acnes).
OC   Bacteria; Actinobacteria; Propionibacteriales; Propionibacteriaceae;
OC   Cutibacterium.
OX   NCBI_TaxID=267747;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16379 / KPA171202;
RX   PubMed=15286373; DOI=10.1126/science.1100330;
RA   Brueggemann H., Henne A., Hoster F., Liesegang H., Wiezer A.,
RA   Strittmatter A., Hujer S., Duerre P., Gottschalk G.;
RT   "The complete genome sequence of Propionibacterium acnes, a commensal of
RT   human skin.";
RL   Science 305:671-673(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC       {ECO:0000305}.
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DR   EMBL; AE017283; AAT83747.1; -; Genomic_DNA.
DR   RefSeq; WP_002516194.1; NZ_CP025935.1.
DR   AlphaFoldDB; Q6A666; -.
DR   SMR; Q6A666; -.
DR   STRING; 267747.PPA2034; -.
DR   EnsemblBacteria; AAT83747; AAT83747; PPA2034.
DR   GeneID; 66621938; -.
DR   KEGG; pac:PPA2034; -.
DR   eggNOG; COG0569; Bacteria.
DR   eggNOG; COG2985; Bacteria.
DR   HOGENOM; CLU_035023_3_0_11; -.
DR   OMA; RDGKNYF; -.
DR   Proteomes; UP000000603; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; -; 1.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR006512; YidE_YbjL.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   Pfam; PF02080; TrkA_C; 1.
DR   SUPFAM; SSF116726; SSF116726; 2.
DR   TIGRFAMs; TIGR01625; YidE_YbjL_dupl; 1.
DR   PROSITE; PS51202; RCK_C; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Repeat; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..525
FT                   /note="Uncharacterized transporter PPA2034"
FT                   /id="PRO_0000208777"
FT   TRANSMEM        7..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        34..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        64..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        92..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        351..370
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        374..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        416..438
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        443..465
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        502..524
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          178..257
FT                   /note="RCK C-terminal 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
FT   DOMAIN          259..341
FT                   /note="RCK C-terminal 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
SQ   SEQUENCE   525 AA;  54629 MW;  E6CA9671FF0744E1 CRC64;
     MTVLTDFLAT HQLLTILIVL ASGALLGQIK FGPLRFGAAG ALFMGLVVGA LDPRFGQNLG
     MIKGLGVVLF CYTVGLAAGS TFLSDLKRQW GLMLAGVVGL AVMAAAGLGL GRLFGLTPAH
     VAGLYAGVLT SPAIDAASMA THGAADTLVG YALSYPVGVV VGLIMVAIIA KRCWPASKDN
     TSMAEAGLTA VSTVVDRETS IRQTPGFNDD QVRMSYLLRD GEMRLATPDD DLHVGDQVLV
     VGNPDDVNRA VEHLGHVSER TLTNERNELD FRRFVVSNPA LVGRTLGSID VRGRTSGKVT
     RVRRGDLDML ARSDIVLQPG DRVLCVVPAH RLSDAADLFG DSEARVSQVD ALSLGLGAAL
     GLLLGALMVA LPRGLQFELG TAAGPLVMGM ILGSIHRTGP LRWQLPHATN AILRQLGLMI
     FLACVGLASG PAFLSQAVSG TGLAVIAVSA VTLVLGGAIV IAAAWCMKLS AQRATGAFAG
     FVGQPAILSY ANSLVNDERI ESAYGALFAL GTVVKILLVQ VIVLV