ID   Y2036_STAES             Reviewed;         230 AA.
AC   Q8CN40;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Uncharacterized oxidoreductase SE_2036;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=SE_2036;
OS   Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12228 / FDA PCI 1200;
RX   PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA   Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA   Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA   Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT   "Genome-based analysis of virulence genes in a non-biofilm-forming
RT   Staphylococcus epidermidis strain (ATCC 12228).";
RL   Mol. Microbiol. 49:1577-1593(2003).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; AE015929; AAO05677.1; -; Genomic_DNA.
DR   RefSeq; NP_765591.1; NC_004461.1.
DR   RefSeq; WP_002438215.1; NZ_WBME01000003.1.
DR   AlphaFoldDB; Q8CN40; -.
DR   SMR; Q8CN40; -.
DR   STRING; 176280.SE_2036; -.
DR   EnsemblBacteria; AAO05677; AAO05677; SE_2036.
DR   KEGG; sep:SE_2036; -.
DR   PATRIC; fig|176280.10.peg.1989; -.
DR   eggNOG; COG4221; Bacteria.
DR   HOGENOM; CLU_010194_2_10_9; -.
DR   OMA; ITGGRNW; -.
DR   Proteomes; UP000001411; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..230
FT                   /note="Uncharacterized oxidoreductase SE_2036"
FT                   /id="PRO_0000300478"
FT   ACT_SITE        152
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   BINDING         10..34
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
FT   BINDING         139
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   230 AA;  24541 MW;  E3CC702EC441CABF CRC64;
     MAKVKEKVAV VTGASSGIGE AIAKKLSQQG ASIVLVGRNE QRLNEIAQQL NTPAKVVSAD
     VTVKSNIDDM LKAVIDHFGH IDIVVNSAGQ SLSSKITDYN VEQWDTMIDV NIKGTLHVLQ
     ATLPYLLKQS SGHIINLASV SGFEPTKTNA VYGATKAAIH AITQSLEKEL ARTGVKVTSI
     SPGMVDTPMT EGTDFGERKK LEAQNIADAV VYALTQPSHV NVNEVTIRPV