ID   Y2043_BURMA             Reviewed;         407 AA.
AC   Q62I47;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Uncharacterized MFS-type transporter BMA2043 {ECO:0000255|HAMAP-Rule:MF_01118};
GN   OrderedLocusNames=BMA2043;
OS   Burkholderia mallei (strain ATCC 23344).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=243160;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23344;
RX   PubMed=15377793; DOI=10.1073/pnas.0403306101;
RA   Nierman W.C., DeShazer D., Kim H.S., Tettelin H., Nelson K.E.,
RA   Feldblyum T.V., Ulrich R.L., Ronning C.M., Brinkac L.M., Daugherty S.C.,
RA   Davidsen T.D., DeBoy R.T., Dimitrov G., Dodson R.J., Durkin A.S.,
RA   Gwinn M.L., Haft D.H., Khouri H.M., Kolonay J.F., Madupu R., Mohammoud Y.,
RA   Nelson W.C., Radune D., Romero C.M., Sarria S., Selengut J., Shamblin C.,
RA   Sullivan S.A., White O., Yu Y., Zafar N., Zhou L., Fraser C.M.;
RT   "Structural flexibility in the Burkholderia mallei genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14246-14251(2004).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01118}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01118}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. YhhS family.
CC       {ECO:0000255|HAMAP-Rule:MF_01118}.
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DR   EMBL; CP000010; AAU49585.1; -; Genomic_DNA.
DR   RefSeq; WP_004185668.1; NC_006348.1.
DR   RefSeq; YP_103623.1; NC_006348.1.
DR   AlphaFoldDB; Q62I47; -.
DR   SMR; Q62I47; -.
DR   STRING; 243160.BMA2043; -.
DR   EnsemblBacteria; AAU49585; AAU49585; BMA2043.
DR   GeneID; 56594948; -.
DR   KEGG; bma:BMA2043; -.
DR   PATRIC; fig|243160.12.peg.2110; -.
DR   eggNOG; COG2814; Bacteria.
DR   HOGENOM; CLU_001265_10_3_4; -.
DR   OMA; CAFVGAR; -.
DR   Proteomes; UP000006693; Chromosome 1.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   HAMAP; MF_01118; MFS_YhhS; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR023008; MFS_YhhS-like.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..407
FT                   /note="Uncharacterized MFS-type transporter BMA2043"
FT                   /id="PRO_1000137229"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        126..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        154..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        258..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        309..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        347..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        369..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
SQ   SEQUENCE   407 AA;  41264 MW;  B1A55D8A2862993E CRC64;
     MSADSADSVP SPRSAFATTL QIVSVVSFTF ICYLTIGLPL AVLPGFVHDE LGFSAIVAGA
     AISVQYFATL ASRPLAGRCA DTLGPKRTVL RGLAACGASG ALLLSAFAFA RWPAASIGLL
     VASRLVLGIG ESLVGTGAIL WGIGRVGTAH NARVISWNGI ATYGALAIGA PVGVAISHAL
     IPAVLGMLVI ALAALGYYLA RLITPVPLVH GERMSYASVL TRVLPHGLGL ALGSAGFGSI
     ATFITLYYAA RHWPNAALSL TVFGTLFIGA RLLFANTIKT HGGFRVAIVS FAFECAGLLM
     LWLAPVPHVA LVGAALTGFG FALIFPALGV EAVALVPPAS RGAALSAYSV FLDLSLGITG
     PLAGYVAGAF GYPQVFLCAA VAAAAGVALS TVLYQRQARL SGSGAAA