Y2045_ARATH
ID Y2045_ARATH Reviewed; 209 AA.
AC O22890;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Putative BTB/POZ domain-containing protein At2g40450;
GN OrderedLocusNames=At2g40450; ORFNames=T2P4.20, T3G21;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP DOMAIN BTB.
RX PubMed=15749712; DOI=10.1074/jbc.m413247200;
RA Gingerich D.J., Gagne J.M., Salter D.W., Hellmann H., Estelle M., Ma L.,
RA Vierstra R.D.;
RT "Cullins 3a and 3b assemble with members of the broad
RT complex/tramtrack/bric-a-brac (BTB) protein family to form essential
RT ubiquitin-protein ligases (E3s) in Arabidopsis.";
RL J. Biol. Chem. 280:18810-18821(2005).
CC -!- FUNCTION: May act as a substrate-specific adapter of an E3 ubiquitin-
CC protein ligase complex (CUL3-RBX1-BTB) which mediates the
CC ubiquitination and subsequent proteasomal degradation of target
CC proteins. {ECO:0000250}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- DOMAIN: The BTB/POZ domain mediates the interaction with some component
CC of ubiquitin ligase complexes. {ECO:0000269|PubMed:15749712}.
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DR EMBL; AC002336; AAB87591.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09832.1; -; Genomic_DNA.
DR PIR; F84829; F84829.
DR RefSeq; NP_181577.1; NM_129606.2.
DR AlphaFoldDB; O22890; -.
DR SMR; O22890; -.
DR BioGRID; 3977; 2.
DR IntAct; O22890; 2.
DR STRING; 3702.AT2G40450.1; -.
DR PaxDb; O22890; -.
DR PRIDE; O22890; -.
DR ProteomicsDB; 232392; -.
DR EnsemblPlants; AT2G40450.1; AT2G40450.1; AT2G40450.
DR GeneID; 818639; -.
DR Gramene; AT2G40450.1; AT2G40450.1; AT2G40450.
DR KEGG; ath:AT2G40450; -.
DR Araport; AT2G40450; -.
DR TAIR; locus:2061873; AT2G40450.
DR eggNOG; KOG1987; Eukaryota.
DR HOGENOM; CLU_004253_9_1_1; -.
DR OMA; AVELMIW; -.
DR OrthoDB; 1393322at2759; -.
DR PhylomeDB; O22890; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:O22890; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O22890; baseline and differential.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.710.10; -; 1.
DR InterPro; IPR044784; At1g01640-like.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR47274; PTHR47274; 1.
DR Pfam; PF00651; BTB; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; SSF54695; 1.
DR PROSITE; PS50097; BTB; 1.
PE 3: Inferred from homology;
KW Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..209
FT /note="Putative BTB/POZ domain-containing protein
FT At2g40450"
FT /id="PRO_0000405999"
FT DOMAIN 24..98
FT /note="BTB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
SQ SEQUENCE 209 AA; 23504 MW; E10751AC78073826 CRC64;
MATQSNKEAF LGGFKKLLNE QWQADVRLKA GDSDETTSIF AHKLVLVARS EVFKKILESD
EFKASSKQME TVTLSEMKHE ELEAFVEFIY RVDGSICSAS LKKHARSLFH AADKYEIPHL
RDLCRNELIS SLNSSNALSI LELAQIPFDK ALNDPAFTTI ITNISTIASG DEFKLFVANH
PNLAVDIMKA SITRLSTSRK ICGYCNRYY
