ID   Y2047_MYCTU             Reviewed;         854 AA.
AC   P9WIH5; L0TB71; P65684; Q93IG5;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 41.
DE   RecName: Full=Uncharacterized protein Rv2047c;
GN   OrderedLocusNames=Rv2047c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- SIMILARITY: Belongs to the PEP-utilizing enzyme family. {ECO:0000305}.
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DR   EMBL; AL123456; CCP44820.1; -; Genomic_DNA.
DR   PIR; F70944; F70944.
DR   RefSeq; NP_216563.1; NC_000962.3.
DR   RefSeq; WP_003410309.1; NZ_NVQJ01000046.1.
DR   AlphaFoldDB; P9WIH5; -.
DR   SMR; P9WIH5; -.
DR   STRING; 83332.Rv2047c; -.
DR   PaxDb; P9WIH5; -.
DR   DNASU; 888529; -.
DR   GeneID; 888529; -.
DR   KEGG; mtu:Rv2047c; -.
DR   PATRIC; fig|83332.111.peg.2282; -.
DR   TubercuList; Rv2047c; -.
DR   eggNOG; COG0451; Bacteria.
DR   eggNOG; COG3848; Bacteria.
DR   OMA; VAHCAWA; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0009274; C:peptidoglycan-based cell wall; HDA:MTBBASE.
DR   GO; GO:0008460; F:dTDP-glucose 4,6-dehydratase activity; IBA:GO_Central.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:InterPro.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR008279; PEP-util_enz_mobile_dom.
DR   InterPro; IPR036637; Phosphohistidine_dom_sf.
DR   Pfam; PF01370; Epimerase; 1.
DR   Pfam; PF00391; PEP-utilizers; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   SUPFAM; SSF52009; SSF52009; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..854
FT                   /note="Uncharacterized protein Rv2047c"
FT                   /id="PRO_0000147101"
SQ   SEQUENCE   854 AA;  91385 MW;  3CC9EDA9408A0E76 CRC64;
     MRIAVTGASG VLGRGLTARL LSQGHEVVGI ARHRPDSWPS SADFIAADIR DATAVESAMT
     GADVVAHCAW VRGRNDHINI DGTANVLKAM AETGTGRIVF TSSGHQPRVE QMLADCGLEW
     VAVRCALIFG RNVDNWVQRL FALPVLPAGY ADRVVQVVHS DDAQRLLVRA LLDTVIDSGP
     VNLAAPGELT FRRIAAALGR PMVPIGSPVL RRVTSFAELE LLHSAPLMDV TLLRDRWGFQ
     PAWNAEECLE DFTLAVRGRI GLGKRTFSLP WRLANIQDLP AVDSPADDGV APRLAGPEGA
     NGEFDTPIDP RFPTYLATNL SEALPGPFSP SSASVTVRGL RAGGVGIAER LRPSGVIQRE
     IAMRTVAVFA HRLYGAITSA HFMAATVPFA KPATIVSNSG FFGPSMASLP IFGAQRPPSE
     SSRARRWLRT LRNIGVFGVN LVGLSAGSPR DTDAYVADVD RLERLAFDNL ATHDDRRLLS
     LILLARDHVV HGWVLASGSF MLCAAFNVLL RGLCGRDTAP AAGPELVSAR SVEAVQRLVA
     AARRDPVVIR LLAEPGERLD KLAVEAPEFH SAVLAELTLI GHRGPAEVEM AATSYADNPE
     LLVRMVAKTL RAVPAPQPPT PVIPLRAKPV ALLAARQLRD REVRRDRMVR AIWVLRALLR
     EYGRRLTEAG VFDTPDDVFY LLVDEIDALP ADVSGLVARR RAEQRRLAGI VPPTVFSGSW
     EPSPSSAAAL AAGDTLRGVG VCGGRVRGRV RIVRPETIDD LQPGEILVAE VTDVGYTAAF
     CYAAAVVTEL GGPMSHAAVV AREFGFPCVV DAQGATRFLP PGALVEVDGA TGEIHVVELA
     SEDGPALPGS DLSR