ID   Y2049_STAEQ             Reviewed;         230 AA.
AC   Q5HLD8;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Uncharacterized oxidoreductase SERP2049;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=SERP2049;
OS   Staphylococcus epidermidis (strain ATCC 35984 / RP62A).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35984 / RP62A;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; CP000029; AAW52889.1; -; Genomic_DNA.
DR   RefSeq; WP_002438215.1; NC_002976.3.
DR   AlphaFoldDB; Q5HLD8; -.
DR   SMR; Q5HLD8; -.
DR   STRING; 176279.SERP2049; -.
DR   EnsemblBacteria; AAW52889; AAW52889; SERP2049.
DR   KEGG; ser:SERP2049; -.
DR   eggNOG; COG4221; Bacteria.
DR   HOGENOM; CLU_010194_2_10_9; -.
DR   OMA; ITGGRNW; -.
DR   OrthoDB; 1261526at2; -.
DR   Proteomes; UP000000531; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..230
FT                   /note="Uncharacterized oxidoreductase SERP2049"
FT                   /id="PRO_0000300479"
FT   ACT_SITE        152
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   BINDING         10..34
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
FT   BINDING         139
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   230 AA;  24541 MW;  E3CC702EC441CABF CRC64;
     MAKVKEKVAV VTGASSGIGE AIAKKLSQQG ASIVLVGRNE QRLNEIAQQL NTPAKVVSAD
     VTVKSNIDDM LKAVIDHFGH IDIVVNSAGQ SLSSKITDYN VEQWDTMIDV NIKGTLHVLQ
     ATLPYLLKQS SGHIINLASV SGFEPTKTNA VYGATKAAIH AITQSLEKEL ARTGVKVTSI
     SPGMVDTPMT EGTDFGERKK LEAQNIADAV VYALTQPSHV NVNEVTIRPV