Y2058_DICDI
ID Y2058_DICDI Reviewed; 553 AA.
AC Q54DS3;
DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=Transmembrane protein DDB_G0292058;
DE Flags: Precursor;
GN ORFNames=DDB_G0292058;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [2]
RP DEVELOPMENTAL STAGE [LARGE SCALE ANALYSIS].
RX PubMed=12963116; DOI=10.1016/s0925-4773(03)00136-9;
RA Muramoto T., Suzuki K., Shimizu H., Kohara Y., Kohriki E., Obara S.,
RA Tanaka Y., Urushihara H.;
RT "Construction of a gamete-enriched gene pool and RNAi-mediated functional
RT analysis in Dictyostelium discoideum.";
RL Mech. Dev. 120:965-975(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Highly enriched in gametes.
CC {ECO:0000269|PubMed:12963116}.
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DR EMBL; AAFI02000187; EAL61385.1; -; Genomic_DNA.
DR RefSeq; XP_629799.1; XM_629797.1.
DR AlphaFoldDB; Q54DS3; -.
DR SMR; Q54DS3; -.
DR PaxDb; Q54DS3; -.
DR EnsemblProtists; EAL61385; EAL61385; DDB_G0292058.
DR GeneID; 8628477; -.
DR KEGG; ddi:DDB_G0292058; -.
DR dictyBase; DDB_G0292058; -.
DR eggNOG; ENOG502RBB3; Eukaryota.
DR HOGENOM; CLU_492987_0_0_1; -.
DR InParanoid; Q54DS3; -.
DR OMA; RFIDHET; -.
DR PhylomeDB; Q54DS3; -.
DR PRO; PR:Q54DS3; -.
DR Proteomes; UP000002195; Chromosome 6.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR040283; DDB_G0292058-like.
DR PANTHER; PTHR31414; PTHR31414; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..553
FT /note="Transmembrane protein DDB_G0292058"
FT /id="PRO_0000393119"
FT TRANSMEM 80..100
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 243..263
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 515..535
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CARBOHYD 162
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 171
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 178
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 195
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 315
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 332
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 351
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 396
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 405
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 462
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 553 AA; 61071 MW; EC05739417BFF2DD CRC64;
MIKINKILSL LIILLIINCN YQFVKADAES KALDIINRYR DIARYTFFTT DGHLEKYPSG
FCGGTTIEDC KWDEYIEAVI LLSGITFIIA AITLIFGIIF WIFRCLCFGG CKPTHGILCP
GPKYDPDIGE GYSKGRVFIL KLVTLIMVAG CVAVFITSLK GNSSVTSGIN NLSDTVFNKT
SYTLEQLIEI SNQLNETKYQ QFDQKQEIQS QLTQLISDGE ELESKGEDIS SNAKDINNIR
TKIIIVGLVF CMVVAGLIGV SALIGLPRIS RAASIALVIL IPFMWIVFSV HYPINSVVAD
ICISYDTTGV QQLSNFTNPI IEQVFEGCQN DNNTISVFED LQSLVNNLLQ NATDTSCDKI
NDACQLAFPR YPNDNPLSVP YQQNVLDCPP TLTCSNTTLS IYLFNTTVHD FNVKCKNAPT
CGDLSTCDPS ILTEVMSCDW VDVSSVNSCS QGGCQYNQQV VNTTKQIMQL YDILTSLTTL
WTDKVVPLIK CSYLMPFIDE VQNIVCVDEV NSLDLLIAPT AVFAILLTGL GITGILGSKR
FNSKYRVKGS RSA