ID   Y2059_STRMU             Reviewed;         341 AA.
AC   Q8DRZ4;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=UPF0324 membrane protein SMU_2059c;
GN   OrderedLocusNames=SMU_2059c;
OS   Streptococcus mutans serotype c (strain ATCC 700610 / UA159).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=210007;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700610 / UA159;
RX   PubMed=12397186; DOI=10.1073/pnas.172501299;
RA   Ajdic D.J., McShan W.M., McLaughlin R.E., Savic G., Chang J., Carson M.B.,
RA   Primeaux C., Tian R., Kenton S., Jia H.G., Lin S.P., Qian Y., Li S.,
RA   Zhu H., Najar F.Z., Lai H., White J., Roe B.A., Ferretti J.J.;
RT   "Genome sequence of Streptococcus mutans UA159, a cariogenic dental
RT   pathogen.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:14434-14439(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0324 family. {ECO:0000305}.
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DR   EMBL; AE014133; AAN59657.1; -; Genomic_DNA.
DR   RefSeq; NP_722351.1; NC_004350.2.
DR   RefSeq; WP_002262368.1; NC_004350.2.
DR   AlphaFoldDB; Q8DRZ4; -.
DR   STRING; 210007.SMU_2059c; -.
DR   EnsemblBacteria; AAN59657; AAN59657; SMU_2059c.
DR   KEGG; smu:SMU_2059c; -.
DR   PATRIC; fig|210007.7.peg.1833; -.
DR   eggNOG; COG2855; Bacteria.
DR   HOGENOM; CLU_033541_2_1_9; -.
DR   OMA; FGLWCAI; -.
DR   PhylomeDB; Q8DRZ4; -.
DR   Proteomes; UP000002512; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018383; UPF0324_pro.
DR   PANTHER; PTHR30106; PTHR30106; 1.
DR   Pfam; PF03601; Cons_hypoth698; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..341
FT                   /note="UPF0324 membrane protein SMU_2059c"
FT                   /id="PRO_0000157461"
FT   TRANSMEM        7..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        28..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        178..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        211..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        254..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        291..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        317..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   341 AA;  36356 MW;  5776F21542E2BF9B CRC64;
     MSLKFQKLSG LVLCFLIALP AWFLGQSFPL VGAPVFAIFL GMLLAIFYKN REHTEAGIAF
     TSKYILQFAV VLLGFGLNLS QVLTVGKTSL PIIVATISSS LLLAFLLQKW FKLDVNTATL
     VGVGSSICGG SAIAATAPVI QADGDEIAQS ISVIFLFNIL AALIFPTLGD MIGLSNHGFA
     LFAGTAVNDT SSVTATAAAW DGLHHSNTLD GATIVKLTRT LAIIPITLGL SFYQVYKTKK
     VGKNQQHTVK LKKVFPMFIL YFILASIITT ILTALGVNPI FFTPLKTLSK FCIVMAMGAI
     GLNTNIVKLV KTGGQAIVLG ASCWIVITLV SLGMQHLLGI W