Y205_MYCTU
ID Y205_MYCTU Reviewed; 367 AA.
AC P9WFM5; L0T4P1; O53656;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 36.
DE RecName: Full=Putative transport protein Rv0205;
GN OrderedLocusNames=Rv0205; ORFNames=MTV033.13;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL123456; CCP42933.1; -; Genomic_DNA.
DR PIR; B70839; B70839.
DR RefSeq; NP_214719.1; NC_000962.3.
DR RefSeq; WP_003899854.1; NZ_NVQJ01000001.1.
DR AlphaFoldDB; P9WFM5; -.
DR STRING; 83332.Rv0205; -.
DR PaxDb; P9WFM5; -.
DR DNASU; 886766; -.
DR GeneID; 886766; -.
DR KEGG; mtu:Rv0205; -.
DR TubercuList; Rv0205; -.
DR eggNOG; COG0628; Bacteria.
DR OMA; WRTLTAY; -.
DR PhylomeDB; P9WFM5; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR InterPro; IPR002549; AI-2E-like.
DR PANTHER; PTHR21716; PTHR21716; 1.
DR Pfam; PF01594; AI-2E_transport; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..367
FT /note="Putative transport protein Rv0205"
FT /id="PRO_0000148317"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 161..181
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 228..248
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 249..269
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 314..334
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 337..357
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 367 AA; 38038 MW; 41EBAABA3ED5B79D CRC64;
MSASLDDASV APLVRKTAAW AWRFLVILAA MVALLWVLNK FEVIVVPVLL ALMLSALLVP
PVDWLDSRGL PHAVAVTLVL LSGFAVLGGI LTFVVSQFIA GLPHLVTEVE RSIDSARRWL
IEGPAHLRGE QIDNAGNAAI EALRNNQAKL TSGALSTAAT ITELVTAAVL VLFTLIFFLY
GGRSIWQYVT KAFPASVRDR VRAAGRAGYA SLIGYARATF LVALTDAAGV GAGLAVMGVP
LALPLASLVF FGAFIPLIGA VVAGFLAVVV ALLAKGIGYA LITVGLLIAV NQLEAHLLQP
LVMGRAVSIH PLAVVLAIAA GGVLAGVVGA LLAVPTVAFF NNAVQVLLGG NPFADVADVS
SDHLTEV