ID   Y2075_MYCTO             Reviewed;         487 AA.
AC   P9WLL4; L0TBE8; Q10683;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Uncharacterized protein MT2135;
GN   OrderedLocusNames=MT2135;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000516; AAK46415.1; -; Genomic_DNA.
DR   PIR; F70765; F70765.
DR   RefSeq; WP_003899158.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WLL4; -.
DR   EnsemblBacteria; AAK46415; AAK46415; MT2135.
DR   KEGG; mtc:MT2135; -.
DR   PATRIC; fig|83331.31.peg.2303; -.
DR   HOGENOM; CLU_631383_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.190; -; 1.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR   SUPFAM; SSF51695; SSF51695; 1.
DR   SUPFAM; SSF56436; SSF56436; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..487
FT                   /note="Uncharacterized protein MT2135"
FT                   /id="PRO_0000427458"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        439..459
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   487 AA;  51580 MW;  C063E0D112AC2154 CRC64;
     MPRARWLQSA ALMGALAVVL ITAAPVAADA YQVPAPPSPT ASCDVISPVA IPCVALGKFA
     DAVAAECRRV GVPDARCVLP LAHRVTQAAR DAYLQSWVHR TARFQDALQD PVPLRETQWL
     GTHNSFNSLS DSFTVSHADS NQQLSLAQQL DIDVRALELD LHYLPRLEGH GAPGVTVCHG
     LGPKNANLGC TVEPLLATVL PQIANWLNAP GHTEEVILLY LEDQLKNASA YESVVATLDQ
     VLRRADGTSL IYRPNPARRA TNGCVPLPLD VSREEIRASG ARAVLVGSCA PGWSAAVFDW
     SGVELESGSN SGYRPYPACD ATYGRGVYAW RLVRYYEDST LATALANPTR PPANPQALTP
     PKVPAMTDCG VNLFGFDQLL PEDGRIQASL WSWAPDEPRA GAGACALQGA DGRWVAASCG
     DPHPAACRDA AGRWTVTPAP VVFAGAALAC TAIGADFTLP RTGNQNARLH AVAGPAGGAW
     VHYLLPP