Y2083_MYCTO
ID Y2083_MYCTO Reviewed; 314 AA.
AC P9WLK2; L0T8R1; Q10691;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 25.
DE RecName: Full=Uncharacterized protein MT2145;
GN OrderedLocusNames=MT2145;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AE000516; AAK46427.1; -; Genomic_DNA.
DR PIR; F70766; F70766.
DR RefSeq; WP_003900461.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WLK2; -.
DR EnsemblBacteria; AAK46427; AAK46427; MT2145.
DR KEGG; mtc:MT2145; -.
DR PATRIC; fig|83331.31.peg.2314; -.
DR HOGENOM; CLU_067537_0_1_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE 4: Predicted;
KW Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..314
FT /note="Uncharacterized protein MT2145"
FT /id="PRO_0000427464"
FT TRANSMEM 23..43
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 98..118
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 165..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..202
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..314
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 314 AA; 30760 MW; 81E9616F4EF6F71E CRC64;
MTSIESHPEQ YWAAAGRPGP VPLALGPVHP GGPTLIDLLM ALFGLSTNAD LGGANADIEG
DDTDRRAHAA DAARKFSANE ANAAEQMQGV GAQGMAQMAS GIGGALSGAL GGVMGPLTQL
PQQAMQAGQG AMQPLMSAMQ QAQGADGLAA VDGARLLDSI GGEPGLGSGA GGGDVGGGGA
GGTTPTGYLG PPPVPTSSPP TTPAGAPTKS ATMPPPGGAS PASAHMGAAG MPMVPPGAMG
ARGEGSGQEK PVEKRVTAPA VPNGQPVKGR LTVPPSAPTT KPTDGKPVVR RRILLPEHKD
FGRIAPDEKT DAGE