ID   Y2083_MYCTU             Reviewed;         314 AA.
AC   P9WLK3; L0T8R1; Q10691;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 28.
DE   RecName: Full=Uncharacterized protein Rv2083;
GN   OrderedLocusNames=Rv2083; ORFNames=MTCY49.22;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AL123456; CCP44858.1; -; Genomic_DNA.
DR   PIR; F70766; F70766.
DR   RefSeq; NP_216599.1; NC_000962.3.
DR   RefSeq; WP_003916935.1; NZ_NVQJ01000061.1.
DR   AlphaFoldDB; P9WLK3; -.
DR   STRING; 83332.Rv2083; -.
DR   PaxDb; P9WLK3; -.
DR   DNASU; 887281; -.
DR   GeneID; 887281; -.
DR   KEGG; mtu:Rv2083; -.
DR   TubercuList; Rv2083; -.
DR   eggNOG; ENOG5032ENV; Bacteria.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..314
FT                   /note="Uncharacterized protein Rv2083"
FT                   /id="PRO_0000103954"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        221..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          165..314
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        188..202
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        285..314
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   314 AA;  30774 MW;  81E97B754EECED1E CRC64;
     MTSIESHPEQ YWAAAGRPGP VPLALGPVHP GGPTLIDLLM ALFGLSTNAD LGGANADIEG
     DDTDRRAHAA DAARKFSANE ANAAEQMQGV GAQGMAQMAS GIGGALSGAL GGVMGPLTQL
     PQQAMQAGQG AMQPLMSAMQ QAQGADGLAA VDGARLLDSI GGEPGLGSGA GGGDVGGGGA
     GGTTPTGYLG PPPVPTSSPP TTPAGAPTKS ATMPPPGGAS PASAHMGAAG MPMVPPGAMG
     ARGEGSGQEK PVEKRLTAPA VPNGQPVKGR LTVPPSAPTT KPTDGKPVVR RRILLPEHKD
     FGRIAPDEKT DAGE