ID   Y2091_MYCTU             Reviewed;         244 AA.
AC   P9WLJ5; L0TA69; P64939; Q10700;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 31.
DE   RecName: Full=Uncharacterized protein Rv2091c;
GN   OrderedLocusNames=Rv2091c; ORFNames=MTCY49.31c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AL123456; CCP44866.1; -; Genomic_DNA.
DR   PIR; F70767; F70767.
DR   RefSeq; NP_216607.1; NC_000962.3.
DR   RefSeq; WP_003410762.1; NZ_NVQJ01000061.1.
DR   AlphaFoldDB; P9WLJ5; -.
DR   SMR; P9WLJ5; -.
DR   STRING; 83332.Rv2091c; -.
DR   PaxDb; P9WLJ5; -.
DR   DNASU; 887469; -.
DR   GeneID; 887469; -.
DR   KEGG; mtu:Rv2091c; -.
DR   TubercuList; Rv2091c; -.
DR   eggNOG; ENOG5033240; Bacteria.
DR   OMA; GQPQWGQ; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; HDA:MTBBASE.
DR   GO; GO:0009274; C:peptidoglycan-based cell wall; HDA:MTBBASE.
DR   InterPro; IPR025637; DUF4333.
DR   Pfam; PF14230; DUF4333; 1.
PE   1: Evidence at protein level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..244
FT                   /note="Uncharacterized protein Rv2091c"
FT                   /id="PRO_0000103961"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..127
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        29..60
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        70..106
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   244 AA;  26020 MW;  2898D0366A89136F CRC64;
     MSGPQGSDPR QPWQPPGQGA DHSSDPTVAA GYPWQQQPTQ EATWQAPAYT PQYQQPADPA
     YPQQYPQPTP GYAQPEQFGA QPTQLGVPGQ YGQYQQPGQY GQPGQYGQPG QYAPPGQYPG
     QYGPYGQSGQ GSKRSVAVIG GVIAVMAVLF IGAVLILGFW APGFFVTTKL DVIKAQAGVQ
     QVLTDETTGY GAKNVKDVKC NNGSDPTVKK GATFECTVSI DGTSKRVTVT FQDNKGTYEV
     GRPQ