ID   Y2092_BACTN             Reviewed;         554 AA.
AC   Q8A5Z4;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Uncharacterized transporter BT_2092;
GN   OrderedLocusNames=BT_2092;
OS   Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 /
OS   CCUG 10774 / NCTC 10582 / VPI-5482 / E50).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=226186;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC   VPI-5482 / E50;
RX   PubMed=12663928; DOI=10.1126/science.1080029;
RA   Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C.,
RA   Hooper L.V., Gordon J.I.;
RT   "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
RL   Science 299:2074-2076(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC       {ECO:0000305}.
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DR   EMBL; AE015928; AAO77199.1; -; Genomic_DNA.
DR   RefSeq; NP_811005.1; NC_004663.1.
DR   RefSeq; WP_008766579.1; NC_004663.1.
DR   AlphaFoldDB; Q8A5Z4; -.
DR   SMR; Q8A5Z4; -.
DR   STRING; 226186.BT_2092; -.
DR   PaxDb; Q8A5Z4; -.
DR   PRIDE; Q8A5Z4; -.
DR   EnsemblBacteria; AAO77199; AAO77199; BT_2092.
DR   GeneID; 60928080; -.
DR   KEGG; bth:BT_2092; -.
DR   PATRIC; fig|226186.12.peg.2153; -.
DR   eggNOG; COG0569; Bacteria.
DR   eggNOG; COG2985; Bacteria.
DR   HOGENOM; CLU_035023_3_1_10; -.
DR   InParanoid; Q8A5Z4; -.
DR   OMA; GPQFFAN; -.
DR   Proteomes; UP000001414; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; -; 2.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR006512; YidE_YbjL.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   Pfam; PF02080; TrkA_C; 2.
DR   SUPFAM; SSF116726; SSF116726; 2.
DR   TIGRFAMs; TIGR01625; YidE_YbjL_dupl; 2.
DR   PROSITE; PS51202; RCK_C; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..554
FT                   /note="Uncharacterized transporter BT_2092"
FT                   /id="PRO_0000208755"
FT   TRANSMEM        13..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        36..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        73..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        161..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        376..395
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        405..422
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        442..464
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        468..490
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          199..281
FT                   /note="RCK C-terminal 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
FT   DOMAIN          282..366
FT                   /note="RCK C-terminal 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
SQ   SEQUENCE   554 AA;  60169 MW;  6866276221DE9E7D CRC64;
     MDWLQSLLWD PSSVAHIVFL YAFVVAAGVY LGKIKIFGVS LGVTFVLFAG ILMGHFGFTA
     DTHILHFIRE FGLILFVFCI GLQVGPSFFS SFKKGGMTLN LLAVGIVVLN IAVALGLYYL
     WNGRVELPMM VGILYGAVTN TPGLGAANEA LNQLSYNGPQ IALGYACAYP LGVVGIIGSI
     IAIRYIFRVN MTKEEESLKT QSGDAHHKPH MMSLEVRNES ISGKTLIEIK EFLGRNFVCS
     RIRHEGHVSI PNHETIFNMG DQLFIVCSEE DAPAITVFIG KEVELDWEKQ DLPMVSRRIL
     VTKPEINGKT LGSMHFRSMY GVNVTRVNRS GMDLFADPNL ILQVGDRVMV VGQQDAVERV
     AGVLGNQLKR LDTPNIVTIF VGIFLGILLG SLPIAFPGMP TPLKLGLAGG PLVVAILIGR
     FGHKLHLVTY TTMSANLMLR EIGIVLFLAS VGIDAGANFV QTVVEGDGLL YVGCGFLITV
     IPLLIIGAIA RLYYKVNYFT LMGLIAGSNT DPPALAYANQ VTSSDAPAVG YSTVYPLSMF
     LRILTGQMIL LAMM