ID   Y2100_MYCTU             Reviewed;         550 AA.
AC   P9WLJ3; L0T8V0; P64945; Q10709;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 34.
DE   RecName: Full=Uncharacterized protein Rv2100;
DE   Flags: Precursor;
GN   OrderedLocusNames=Rv2100; ORFNames=MTCY49.40;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SIMILARITY: To M.tuberculosis Rv3776. {ECO:0000305}.
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DR   EMBL; AL123456; CCP44875.1; -; Genomic_DNA.
DR   PIR; G70768; G70768.
DR   RefSeq; NP_216616.1; NC_000962.3.
DR   RefSeq; WP_003900464.1; NC_000962.3.
DR   AlphaFoldDB; P9WLJ3; -.
DR   STRING; 83332.Rv2100; -.
DR   PaxDb; P9WLJ3; -.
DR   DNASU; 888454; -.
DR   GeneID; 888454; -.
DR   KEGG; mtu:Rv2100; -.
DR   TubercuList; Rv2100; -.
DR   eggNOG; COG1403; Bacteria.
DR   OMA; SEITWRT; -.
DR   PhylomeDB; P9WLJ3; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0009274; C:peptidoglycan-based cell wall; HDA:MTBBASE.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   CDD; cd00085; HNHc; 1.
DR   InterPro; IPR003870; DUF222.
DR   InterPro; IPR003615; HNH_nuc.
DR   Pfam; PF02720; DUF222; 1.
DR   SMART; SM00507; HNHc; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal.
FT   SIGNAL          1..13
FT                   /evidence="ECO:0000255"
FT   CHAIN           14..550
FT                   /note="Uncharacterized protein Rv2100"
FT                   /id="PRO_0000014124"
FT   REGION          312..358
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   550 AA;  58935 MW;  B68F18EC4188A7CE CRC64;
     MAGALFEPSF AAAHPAGLLR RPVTRTVVLS VAATSIAHMF EISLPDPTEL CRSDDGALVA
     AIEDCARVEA AASARRLSAI AELTGRRTGA DQRADWACDF WDCAAAEVAA ALTISHGKAS
     GQMHLSLALN RLPQVAALFL AGHLGARLFS IIAWRTYLVR DPHALSLLDA ALAEHAGAWG
     PLSAPKLEKA IDSWIDRYDP GALRRSRISA RTRDLCIGDP DEDAGTAALW GRLYATDAAM
     LDRRLTEMAH GVCEDDPRTL AQRRADALGA LAAGADHLAC GCGKPDCPSG AGNDERAAGV
     VIHVVADASA LDAQPDPHLS GDEPPSRPLT PETTLFEALT PDPEPDPPAT HAPAELITTG
     GGVVPAPLLA ELIRGGATIS QVRHPGDLAA EPHYRPSAKL AEFVRMRDLT CRFPGCDVPA
     EFCDIDHSAP WPLGPTHPSN LKCACRKHHL LKTFWTGWRD VQLPDGTVIW TAPNGHTYTT
     HPGSRIFFPT WHTTTAELPQ TSTAAVNVDA RGLMMPRRRR TRAAELAHRI NAERALNDAY
     MAERNKPPSF