ID   Y2125_METS4             Reviewed;         269 AA.
AC   B0UBJ1;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Putative hydro-lyase M446_2125 {ECO:0000255|HAMAP-Rule:MF_01830};
DE            EC=4.2.1.- {ECO:0000255|HAMAP-Rule:MF_01830};
GN   OrderedLocusNames=M446_2125;
OS   Methylobacterium sp. (strain 4-46).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Methylobacteriaceae; Methylobacterium.
OX   NCBI_TaxID=426117;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=4-46;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Marx C.J., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium sp. 4-46.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the D-glutamate cyclase family.
CC       {ECO:0000255|HAMAP-Rule:MF_01830}.
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DR   EMBL; CP000943; ACA16587.1; -; Genomic_DNA.
DR   RefSeq; WP_012331996.1; NC_010511.1.
DR   AlphaFoldDB; B0UBJ1; -.
DR   SMR; B0UBJ1; -.
DR   STRING; 426117.M446_2125; -.
DR   PRIDE; B0UBJ1; -.
DR   EnsemblBacteria; ACA16587; ACA16587; M446_2125.
DR   KEGG; met:M446_2125; -.
DR   eggNOG; COG4336; Bacteria.
DR   HOGENOM; CLU_059759_0_0_5; -.
DR   OMA; NVPMYKT; -.
DR   OrthoDB; 1432388at2; -.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   HAMAP; MF_01830; Hydro_lyase; 1.
DR   InterPro; IPR009906; D-Glu_cyclase.
DR   InterPro; IPR038021; Putative_hydro-lyase.
DR   InterPro; IPR016938; UPF0317.
DR   Pfam; PF07286; DUF1445; 1.
DR   PIRSF; PIRSF029755; UCP029755; 1.
DR   SUPFAM; SSF160920; SSF160920; 1.
PE   3: Inferred from homology;
KW   Lyase.
FT   CHAIN           1..269
FT                   /note="Putative hydro-lyase M446_2125"
FT                   /id="PRO_0000379845"
SQ   SEQUENCE   269 AA;  29133 MW;  EC4FD0548210C29F CRC64;
     MTFLRNPADR ARLTGHEARL ACRRGEIVGS TAGLAHGYVQ ANLAVLPKDL ATDFLLFAQR
     NPKPCPIIGV SAPGDRRIPE LGEDLDIATD VSGYRVWRHG EMVEERLDVA DLWRDDLVAF
     AIGCSFSFEA AMVEDGLPLR HVEMGVRVPM YRTTVPCRPA GPFAGPMVVS MRPLTPAQAI
     RAVQITSRFP AVHGAPVHLG LPEAIGIRDL GRPDYGDPVR VAPDEIPVFW ACGVTPQSVI
     AASKPSFAIT HAPGAMLVTD RRNSEFAVL