ID   Y2132_NATPD             Reviewed;         241 AA.
AC   Q3IRT5;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=UPF0173 metal-dependent hydrolase NP_2132A {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=NP_2132A;
OS   Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM
OS   8858 / NBRC 14720 / NCIMB 2260 / Gabara) (Halobacterium pharaonis).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Natronomonas.
OX   NCBI_TaxID=348780;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB
RC   2260 / Gabara;
RX   PubMed=16169924; DOI=10.1101/gr.3952905;
RA   Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J.,
RA   Oesterhelt D.;
RT   "Living with two extremes: conclusions from the genome sequence of
RT   Natronomonas pharaonis.";
RL   Genome Res. 15:1336-1343(2005).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; CR936257; CAI49157.1; -; Genomic_DNA.
DR   RefSeq; WP_011322785.1; NC_007426.1.
DR   AlphaFoldDB; Q3IRT5; -.
DR   SMR; Q3IRT5; -.
DR   STRING; 348780.NP_2132A; -.
DR   EnsemblBacteria; CAI49157; CAI49157; NP_2132A.
DR   GeneID; 3701360; -.
DR   KEGG; nph:NP_2132A; -.
DR   eggNOG; arCOG00497; Archaea.
DR   HOGENOM; CLU_070010_4_0_2; -.
DR   OMA; WHGHSTW; -.
DR   OrthoDB; 76909at2157; -.
DR   Proteomes; UP000002698; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..241
FT                   /note="UPF0173 metal-dependent hydrolase NP_2132A"
FT                   /id="PRO_0000367237"
SQ   SEQUENCE   241 AA;  25575 MW;  03541ABDE0C5CC21 CRC64;
     MELTWYGHST WHVSVGSTDL LIDPFFGNPK TDLEPSDLDS PDYVLLTHGH EDHVAHAGAF
     SDATLVATPE LVGYAEDNFG FEDAVGGMGM NLGGSVECGD AWVTMTRADH SNGIETGYET
     SAGMPAGFVV SESEPQRASD AANTAFYHAG DTSLMVEMRE VIGPYLEPDF AALPAGDHFT
     MGPEQAAIAA DWLGADYAAP MHYDTFPPIE IDTDEFVDAL NATGADAEAV VLDGDESFTL
     G