ID   Y2141_BORPA             Reviewed;         571 AA.
AC   Q7W8J2;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Uncharacterized transporter BPP2141;
GN   OrderedLocusNames=BPP2141;
OS   Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=257311;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12822 / ATCC BAA-587 / NCTC 13253;
RX   PubMed=12910271; DOI=10.1038/ng1227;
RA   Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R.,
RA   Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L.,
RA   Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A.,
RA   Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA   Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T.,
RA   Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S.,
RA   Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E.,
RA   Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M.,
RA   Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S.,
RA   Barrell B.G., Maskell D.J.;
RT   "Comparative analysis of the genome sequences of Bordetella pertussis,
RT   Bordetella parapertussis and Bordetella bronchiseptica.";
RL   Nat. Genet. 35:32-40(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC       {ECO:0000305}.
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DR   EMBL; BX640429; CAE37441.1; -; Genomic_DNA.
DR   RefSeq; WP_010928386.1; NC_002928.3.
DR   AlphaFoldDB; Q7W8J2; -.
DR   PRIDE; Q7W8J2; -.
DR   EnsemblBacteria; CAE37441; CAE37441; BPP2141.
DR   KEGG; bpa:BPP2141; -.
DR   HOGENOM; CLU_035023_2_2_4; -.
DR   OMA; AMWLIRL; -.
DR   Proteomes; UP000001421; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR006512; YidE_YbjL.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   SUPFAM; SSF116726; SSF116726; 2.
DR   TIGRFAMs; TIGR01625; YidE_YbjL_dupl; 1.
DR   PROSITE; PS51202; RCK_C; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..571
FT                   /note="Uncharacterized transporter BPP2141"
FT                   /id="PRO_0000208761"
FT   TRANSMEM        10..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        36..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        166..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        388..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        411..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        446..465
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        480..502
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        509..531
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        546..568
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          294..378
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
SQ   SEQUENCE   571 AA;  59877 MW;  7BDCF3359C1F5A96 CRC64;
     MTIEALADVV RLHPELALFA AIVFGHFIGK IEIRKVSLGT VVGTLIAGMI LGLLFEPEIP
     DLLKWAFFDL FLFAVGYSAG PQFFASLKRE ALPQMALAVV VSCTGLAAAI AMVALFRFDP
     GLSAGLVSGS MTQSAALGSA LSAIAAMDVD EATRALLTAH APLADATTYI FGEVGLILFV
     TVVAPRLLKV DLRQVAREAE AELQARTDED DAALWDQAPL SLRTYRLENA ELDQRTVHEF
     ERRYAAGRLT VTGIRRGDQL LRDVGADARL ALGDIVLVAS RRAGVVGAAL EVGTEVDDQE
     LLSEPMVRAS IVLTRREMAG KTLGELARGA ARGLFLDSLH RGESTLPRAM GTRVQRGDVF
     KLTGSRAAIA TAARNLGFIE HDQGRTDLVY LAGGVVVGIL FGLLQVRLTG VPLGLGTSGG
     VLVVGLVAGW LYSRYPVVGH IPEPALRLLS DVGLIVFIAA IGLAAGPHAV QAIHEGGIAL
     FAKLVGAGVV VTLAGPIAGL LLGHYVLKLP PVALLPGIAG AQTTVATLNA LKERGGSDVY
     AIGFTVPFAV SNVLITLWGP VIVACAVALS R