Y2143_ACET2
ID Y2143_ACET2 Reviewed; 113 AA.
AC A3DHB8;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Nucleoid-associated protein Cthe_2143 {ECO:0000255|HAMAP-Rule:MF_00274};
GN OrderedLocusNames=Cthe_2143;
OS Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC
OS 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Clostridium thermocellum).
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Oscillospiraceae;
OC Acetivibrio.
OX NCBI_TaxID=203119;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL
RC B-4536 / VPI 7372;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Wu J.H.D.,
RA Newcomb M., Richardson P.;
RT "Complete sequence of Clostridium thermocellum ATCC 27405.";
RL Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS), AND SUBUNIT.
RC STRAIN=ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL
RC B-4536 / VPI 7372;
RG Southeast collaboratory for structural genomics (SECSG);
RT "Conserved hypothetical protein cth-383 from Clostridium thermocellum.";
RL Submitted (JUL-2011) to the PDB data bank.
CC -!- FUNCTION: Binds to DNA and alters its conformation. May be involved in
CC regulation of gene expression, nucleoid organization and DNA
CC protection. {ECO:0000255|HAMAP-Rule:MF_00274}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00274,
CC ECO:0000269|Ref.2}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC Rule:MF_00274}.
CC -!- SIMILARITY: Belongs to the YbaB/EbfC family. {ECO:0000255|HAMAP-
CC Rule:MF_00274}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000568; ABN53347.1; -; Genomic_DNA.
DR RefSeq; WP_003514292.1; NC_009012.1.
DR PDB; 1YBX; X-ray; 1.80 A; A/B=1-113.
DR PDBsum; 1YBX; -.
DR AlphaFoldDB; A3DHB8; -.
DR SMR; A3DHB8; -.
DR STRING; 203119.Cthe_2143; -.
DR EnsemblBacteria; ABN53347; ABN53347; Cthe_2143.
DR KEGG; cth:Cthe_2143; -.
DR eggNOG; COG0718; Bacteria.
DR HOGENOM; CLU_140930_1_0_9; -.
DR OMA; MGNMMKQ; -.
DR OrthoDB; 1883809at2; -.
DR EvolutionaryTrace; A3DHB8; -.
DR Proteomes; UP000002145; Chromosome.
DR GO; GO:0043590; C:bacterial nucleoid; IEA:UniProtKB-UniRule.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1310.10; -; 1.
DR HAMAP; MF_00274; DNA_YbaB_EbfC; 1.
DR InterPro; IPR036894; YbaB-like_sf.
DR InterPro; IPR004401; YbaB/EbfC.
DR PANTHER; PTHR33449; PTHR33449; 1.
DR Pfam; PF02575; YbaB_DNA_bd; 1.
DR PIRSF; PIRSF004555; UCP004555; 1.
DR SUPFAM; SSF82607; SSF82607; 1.
DR TIGRFAMs; TIGR00103; DNA_YbaB_EbfC; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; DNA-binding; Reference proteome.
FT CHAIN 1..113
FT /note="Nucleoid-associated protein Cthe_2143"
FT /id="PRO_1000003732"
FT HELIX 14..36
FT /evidence="ECO:0007829|PDB:1YBX"
FT STRAND 38..43
FT /evidence="ECO:0007829|PDB:1YBX"
FT TURN 44..47
FT /evidence="ECO:0007829|PDB:1YBX"
FT STRAND 48..53
FT /evidence="ECO:0007829|PDB:1YBX"
FT STRAND 58..63
FT /evidence="ECO:0007829|PDB:1YBX"
FT HELIX 65..67
FT /evidence="ECO:0007829|PDB:1YBX"
FT HELIX 73..102
FT /evidence="ECO:0007829|PDB:1YBX"
SQ SEQUENCE 113 AA; 11996 MW; C027B079CC12C108 CRC64;
MAKGGFPGFG GNINNLVKQA QKMQRDMERV QEELKEKTVE ASAGGGAVTV VATGRKDIKE
ITIKPEVVDP DDVEMLQDLI LAAVNEALRK ADEMVTAEIS KITGGLGGIP GLF
