ID   Y2154_ENTFA             Reviewed;         183 AA.
AC   Q832R4;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=UPF0397 protein EF_2154 {ECO:0000255|HAMAP-Rule:MF_01572};
GN   OrderedLocusNames=EF_2154;
OS   Enterococcus faecalis (strain ATCC 700802 / V583).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=226185;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700802 / V583;
RX   PubMed=12663927; DOI=10.1126/science.1080613;
RA   Paulsen I.T., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R.,
RA   Read T.D., Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA   Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C.,
RA   DeBoy R.T., Durkin S.A., Kolonay J.F., Madupu R., Nelson W.C.,
RA   Vamathevan J.J., Tran B., Upton J., Hansen T., Shetty J., Khouri H.M.,
RA   Utterback T.R., Radune D., Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT   "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT   faecalis.";
RL   Science 299:2071-2074(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01572};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01572}.
CC   -!- SIMILARITY: Belongs to the UPF0397 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01572}.
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DR   EMBL; AE016830; AAO81887.1; -; Genomic_DNA.
DR   RefSeq; NP_815817.1; NC_004668.1.
DR   RefSeq; WP_002356937.1; NZ_KE136528.1.
DR   AlphaFoldDB; Q832R4; -.
DR   SMR; Q832R4; -.
DR   STRING; 226185.EF_2154; -.
DR   EnsemblBacteria; AAO81887; AAO81887; EF_2154.
DR   GeneID; 60894317; -.
DR   KEGG; efa:EF2154; -.
DR   PATRIC; fig|226185.45.peg.1374; -.
DR   eggNOG; COG4720; Bacteria.
DR   HOGENOM; CLU_120023_0_0_9; -.
DR   OMA; WWSWVIA; -.
DR   Proteomes; UP000001415; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01572; UPF0397; 1.
DR   InterPro; IPR009825; ECF_substrate-spec-like.
DR   InterPro; IPR022914; UPF0397.
DR   Pfam; PF07155; ECF-ribofla_trS; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..183
FT                   /note="UPF0397 protein EF_2154"
FT                   /id="PRO_0000260792"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        115..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
SQ   SEQUENCE   183 AA;  19659 MW;  D2041856FA233A51 CRC64;
     MKEKMSVKTI VAIGIGSAVF VILGRFVVIP TGIPNTNLET SYPFLALMSV VFGPVAGGLI
     GLIGHTLKDF TTYGSAWWSW IICSGIIGII FGFAGRKMDL QHGEFTTNDM VRFNIFQAFG
     NIVVWGLIAP SLDILIYSEP ASKVFTQGVF ATVSNIVAVG IIGTLLMKAY ASTRTKKGSL
     SKD