ID   Y2157_STRA5             Reviewed;         288 AA.
AC   Q8DWQ7;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   13-APR-2004, sequence version 2.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Putative sugar uptake protein SAG2157;
GN   OrderedLocusNames=SAG2157;
OS   Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=208435;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-611 / 2603 V/R;
RX   PubMed=12200547; DOI=10.1073/pnas.182380799;
RA   Tettelin H., Masignani V., Cieslewicz M.J., Eisen J.A., Peterson S.N.,
RA   Wessels M.R., Paulsen I.T., Nelson K.E., Margarit I., Read T.D.,
RA   Madoff L.C., Wolf A.M., Beanan M.J., Brinkac L.M., Daugherty S.C.,
RA   DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Lewis M.R., Radune D.,
RA   Fedorova N.B., Scanlan D., Khouri H.M., Mulligan S., Carty H.A.,
RA   Cline R.T., Van Aken S.E., Gill J., Scarselli M., Mora M., Iacobini E.T.,
RA   Brettoni C., Galli G., Mariani M., Vegni F., Maione D., Rinaudo D.,
RA   Rappuoli R., Telford J.L., Kasper D.L., Grandi G., Fraser C.M.;
RT   "Complete genome sequence and comparative genomic analysis of an emerging
RT   human pathogen, serotype V Streptococcus agalactiae.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:12391-12396(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GRP transporter (TC 2.A.7.5) family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAN01015.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE009948; AAN01015.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_689142.1; NC_004116.1.
DR   RefSeq; WP_000398683.1; NC_004116.1.
DR   AlphaFoldDB; Q8DWQ7; -.
DR   SMR; Q8DWQ7; -.
DR   STRING; 208435.SAG2157; -.
DR   DNASU; 1014968; -.
DR   EnsemblBacteria; AAN01015; AAN01015; SAG2157.
DR   GeneID; 66886892; -.
DR   KEGG; sag:SAG2157; -.
DR   PATRIC; fig|208435.3.peg.2160; -.
DR   HOGENOM; CLU_076024_0_0_9; -.
DR   Proteomes; UP000000821; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR010651; Sugar_transport.
DR   PANTHER; PTHR16119; PTHR16119; 2.
DR   Pfam; PF06800; Sugar_transport; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..288
FT                   /note="Putative sugar uptake protein SAG2157"
FT                   /id="PRO_0000213662"
FT   TRANSMEM        4..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        33..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        55..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        117..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        154..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        181..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        207..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        234..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        268..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   288 AA;  31077 MW;  DCE5E7C1B2C7BEC6 CRC64;
     MEGLLIALIP MFAWGSIGFV SNKIGGRPNQ QTFGMTLGAL LFAIIVWLFK QPEMTASLWI
     FGILGGILWS VGQNGQFQAM KYMGVSVANP LSSGAQLVGG SLVGALVFHE WTKPIQFILG
     LTALTLLVIG FYFSSKRDVS EQALATHQEF SKGFATIAYS TVGYISYAVL FNNIMKFDAM
     AVILPMAVGM CLGAICFMKF RVNFEAVVVK NMITGLMWGV GNVFMLLAAA KAGLAIAFSF
     SQLGVIISII GGILFLGETK TKKEQKWVVM GILCFVMGAI LLGIVKSY