ID   Y2160_PYRAE             Reviewed;         225 AA.
AC   Q8ZVR4;
DT   02-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=UPF0173 metal-dependent hydrolase PAE2160 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=PAE2160;
OS   Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP
OS   104966 / NBRC 100827 / IM2).
OC   Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC   Pyrobaculum.
OX   NCBI_TaxID=178306;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2;
RX   PubMed=11792869; DOI=10.1073/pnas.241636498;
RA   Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I.,
RA   Miller J.H.;
RT   "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum
RT   aerophilum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; AE009441; AAL63992.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8ZVR4; -.
DR   SMR; Q8ZVR4; -.
DR   STRING; 178306.PAE2160; -.
DR   EnsemblBacteria; AAL63992; AAL63992; PAE2160.
DR   KEGG; pai:PAE2160; -.
DR   PATRIC; fig|178306.9.peg.1598; -.
DR   eggNOG; arCOG00497; Archaea.
DR   HOGENOM; CLU_070010_4_0_2; -.
DR   InParanoid; Q8ZVR4; -.
DR   OMA; WHGHSTW; -.
DR   Proteomes; UP000002439; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..225
FT                   /note="UPF0173 metal-dependent hydrolase PAE2160"
FT                   /id="PRO_0000156397"
SQ   SEQUENCE   225 AA;  24538 MW;  656B893F7CC95E64 CRC64;
     MQIKWFGHAA FMVEVGGARL LIDPWISNPL SPATPQDVIN ARPTHIMITH DHFDHMGEAV
     DIAKATKAPI VGTFELTLEV AEKGIPEAQT MPMNIGGTIK LGDGIELYMT PALHTANRGA
     PSGFVIATPE GTVYHAGDTA LFRDMELIGE LYDIDVALLP IGSVFTMGPR EAAIATQLLR
     ARRVVPMHYN TFPLIKQDPE DFKARVEAVS RAKVFVMKPG DVLKV