ID   Y2168_ARATH             Reviewed;         532 AA.
AC   Q9ZU96; Q8LFC8;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Ankyrin repeat-containing protein At2g01680;
GN   OrderedLocusNames=At2g01680; ORFNames=T8O11.15;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AC006069; AAD12703.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC05484.1; -; Genomic_DNA.
DR   EMBL; AY084921; AAM61483.1; -; mRNA.
DR   PIR; G84427; G84427.
DR   RefSeq; NP_565274.1; NM_126229.4.
DR   AlphaFoldDB; Q9ZU96; -.
DR   SMR; Q9ZU96; -.
DR   BioGRID; 100; 39.
DR   IntAct; Q9ZU96; 39.
DR   STRING; 3702.AT2G01680.1; -.
DR   iPTMnet; Q9ZU96; -.
DR   PaxDb; Q9ZU96; -.
DR   PRIDE; Q9ZU96; -.
DR   ProteomicsDB; 242861; -.
DR   EnsemblPlants; AT2G01680.1; AT2G01680.1; AT2G01680.
DR   GeneID; 814697; -.
DR   Gramene; AT2G01680.1; AT2G01680.1; AT2G01680.
DR   KEGG; ath:AT2G01680; -.
DR   Araport; AT2G01680; -.
DR   TAIR; locus:2065434; AT2G01680.
DR   eggNOG; KOG0504; Eukaryota.
DR   HOGENOM; CLU_000134_49_0_1; -.
DR   InParanoid; Q9ZU96; -.
DR   OMA; MAMQNDA; -.
DR   OrthoDB; 432076at2759; -.
DR   PhylomeDB; Q9ZU96; -.
DR   PRO; PR:Q9ZU96; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q9ZU96; baseline and differential.
DR   Genevisible; Q9ZU96; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0008157; F:protein phosphatase 1 binding; IBA:GO_Central.
DR   GO; GO:0019888; F:protein phosphatase regulator activity; IBA:GO_Central.
DR   GO; GO:0035304; P:regulation of protein dephosphorylation; IBA:GO_Central.
DR   Gene3D; 1.25.40.20; -; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR026961; PGG_dom.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 2.
DR   Pfam; PF13962; PGG; 1.
DR   SMART; SM00248; ANK; 6.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 2.
PE   2: Evidence at transcript level;
KW   ANK repeat; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..532
FT                   /note="Ankyrin repeat-containing protein At2g01680"
FT                   /id="PRO_0000305190"
FT   TRANSMEM        354..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        396..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        436..456
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        467..487
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REPEAT          9..38
FT                   /note="ANK 1"
FT   REPEAT          58..89
FT                   /note="ANK 2"
FT   REPEAT          93..122
FT                   /note="ANK 3"
FT   REPEAT          127..156
FT                   /note="ANK 4"
FT   REPEAT          161..190
FT                   /note="ANK 5"
FT   REPEAT          195..224
FT                   /note="ANK 6"
FT   REPEAT          229..259
FT                   /note="ANK 7"
FT   CONFLICT        45
FT                   /note="C -> S (in Ref. 3; AAM61483)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   532 AA;  58833 MW;  74D6897F794F4B28 CRC64;
     MEMKQMKFLT HQAFFSSVRS GDLSQLQQLV DNLTGDELID ESSPCSAVAE LMSVQNDAGE
     TAVYISAAEN LEDIFRYLIR FSSLETVKIR SKSDMNAFHV AAKRGHLGIV KELLRLWPEL
     CRICDASNTS PLYAAAVQDH LEIVNAMLDV DPSCAMIVRK NGKTSLHTAG RYGLLRIVKA
     LIEKDAAIVG VKDKKGQTAL HMAVKGRSLE VVEEILQADY TILNERDRKG NTALHIATRK
     ARPQITSLLL TFTAIEVNAI NNQKETAMDL ADKLQYSESA LEINEALVEA GAKHGRFIGR
     EDEARALKRA VSDIKHEVQS QLLQNEKTNR RVSGIAKELR KLHREAVQNT TNSITVVAVL
     FASIAFLAIF NLPGQYFTEG SHVGQANIAG RTGFRVFCLL NATSLFISLA VVVVQITLVA
     WDTRAQKKVV SVVNKLMWAA CACTFGAFLA IAFAVVGKGN SWMAITITLL GAPILVGTLA
     SMCYFVFRQR FRSGNDSQRR IRRGSSKSFS WSYSHHVSDF EDESDFEKII AL