Y217_VIBCH
ID Y217_VIBCH Reviewed; 224 AA.
AC Q9KVC9;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=UPF0758 protein VC_0217;
GN OrderedLocusNames=VC_0217;
OS Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=243277;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX PubMed=10952301; DOI=10.1038/35020000;
RA Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT cholerae.";
RL Nature 406:477-483(2000).
CC -!- SIMILARITY: Belongs to the UPF0758 family. {ECO:0000305}.
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DR EMBL; AE003852; AAF93393.1; -; Genomic_DNA.
DR PIR; C82351; C82351.
DR RefSeq; NP_229874.1; NC_002505.1.
DR RefSeq; WP_000053959.1; NZ_LT906614.1.
DR AlphaFoldDB; Q9KVC9; -.
DR SMR; Q9KVC9; -.
DR STRING; 243277.VC_0217; -.
DR PRIDE; Q9KVC9; -.
DR DNASU; 2614562; -.
DR EnsemblBacteria; AAF93393; AAF93393; VC_0217.
DR GeneID; 57738954; -.
DR KEGG; vch:VC_0217; -.
DR PATRIC; fig|243277.26.peg.199; -.
DR eggNOG; COG2003; Bacteria.
DR HOGENOM; CLU_073529_0_2_6; -.
DR OMA; HEEFWII; -.
DR BioCyc; VCHO:VC0217-MON; -.
DR Proteomes; UP000000584; Chromosome 1.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd08071; MPN_DUF2466; 1.
DR InterPro; IPR037518; MPN.
DR InterPro; IPR025657; RadC_JAB.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR001405; UPF0758.
DR InterPro; IPR020891; UPF0758_CS.
DR PANTHER; PTHR30471; PTHR30471; 1.
DR Pfam; PF04002; RadC; 1.
DR SUPFAM; SSF47781; SSF47781; 1.
DR TIGRFAMs; TIGR00608; radc; 1.
DR PROSITE; PS50249; MPN; 1.
DR PROSITE; PS01302; UPF0758; 1.
PE 3: Inferred from homology;
KW Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome;
KW Zinc.
FT CHAIN 1..224
FT /note="UPF0758 protein VC_0217"
FT /id="PRO_0000190749"
FT DOMAIN 102..224
FT /note="MPN"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 173..186
FT /note="JAMM motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 173
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 175
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 186
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
SQ SEQUENCE 224 AA; 25246 MW; 3A212E369E9CCA6F CRC64;
MSLKQLPTES MPREKLLQRG PQSLSDAELL AIFLRTGTQG MNVLALADLL LRDFGSLRAL
FCASKEQFCR HKGLGEAKFV QLQAVLEMTQ RYLAETLKRG DALTSPQQTK LYLSSVLRDR
QREAFYILFL DNQHRVIRDE ILFEGTIDAA SVYPREVVKR ALHHNAAAVI LAHNHPSGVA
EPSQADRRIT DRLRDALGLV EIRVLDHFVV GDGEVVSFAE RGWI
