ID   Y2197_MYCTO             Reviewed;         214 AA.
AC   P9WLI8; L0T8W8; Q10389;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Uncharacterized protein MT2253;
GN   OrderedLocusNames=MT2253;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000516; AAK46539.1; -; Genomic_DNA.
DR   PIR; F70784; F70784.
DR   RefSeq; WP_003899213.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WLI8; -.
DR   EnsemblBacteria; AAK46539; AAK46539; MT2253.
DR   KEGG; mtc:MT2253; -.
DR   PATRIC; fig|83331.31.peg.2428; -.
DR   HOGENOM; CLU_112435_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR024381; DUF2561.
DR   Pfam; PF10812; DUF2561; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..214
FT                   /note="Uncharacterized protein MT2253"
FT                   /id="PRO_0000427471"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          96..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   214 AA;  22480 MW;  8315A7953AE17C79 CRC64;
     MVSRYSAYRR GPDVISPDVI DRILVGACAA VWLVFTGVSV AAAVALMDLG RGFHEMAGNP
     HTTWVLYAVI VVSALVIVGA IPVLLRARRM AEAEPATRPT GASVRGGRSI GSGHPAKRAV
     AESAPVQHAD AFEVAAEWSS EAVDRIWLRG TVVLTSAIGI ALIAVAAATY LMAVGHDGPS
     WISYGLAGVV TAGMPVIEWL YARQLRRVVA PQSS