Y2197_MYCTU
ID Y2197_MYCTU Reviewed; 214 AA.
AC P9WLI9; L0T8W8; Q10389;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 32.
DE RecName: Full=Uncharacterized protein Rv2197c;
GN OrderedLocusNames=Rv2197c; ORFNames=MTCY190.08c;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AL123456; CCP44974.1; -; Genomic_DNA.
DR PIR; F70784; F70784.
DR RefSeq; NP_216713.1; NC_000962.3.
DR RefSeq; WP_003899213.1; NZ_NVQJ01000008.1.
DR AlphaFoldDB; P9WLI9; -.
DR STRING; 83332.Rv2197c; -.
DR PaxDb; P9WLI9; -.
DR DNASU; 887213; -.
DR GeneID; 887213; -.
DR KEGG; mtu:Rv2197c; -.
DR TubercuList; Rv2197c; -.
DR eggNOG; ENOG50316TG; Bacteria.
DR OMA; PWYFLRE; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR024381; DUF2561.
DR Pfam; PF10812; DUF2561; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..214
FT /note="Uncharacterized protein Rv2197c"
FT /id="PRO_0000103971"
FT TRANSMEM 23..43
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 96..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 214 AA; 22480 MW; 8315A7953AE17C79 CRC64;
MVSRYSAYRR GPDVISPDVI DRILVGACAA VWLVFTGVSV AAAVALMDLG RGFHEMAGNP
HTTWVLYAVI VVSALVIVGA IPVLLRARRM AEAEPATRPT GASVRGGRSI GSGHPAKRAV
AESAPVQHAD AFEVAAEWSS EAVDRIWLRG TVVLTSAIGI ALIAVAAATY LMAVGHDGPS
WISYGLAGVV TAGMPVIEWL YARQLRRVVA PQSS
