ID   Y2199_YERPE             Reviewed;         256 AA.
AC   Q8ZEH4; Q0WEW8;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=UPF0259 membrane protein YPO2199/y2042/YP_1997 {ECO:0000255|HAMAP-Rule:MF_01067};
GN   OrderedLocusNames=YPO2199, y2042, YP_1997;
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM10+ / Biovar Mediaevalis;
RX   PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA   Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA   Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01067}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01067}.
CC   -!- SIMILARITY: Belongs to the UPF0259 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01067}.
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DR   EMBL; AL590842; CAL20828.1; -; Genomic_DNA.
DR   EMBL; AE009952; AAM85607.1; -; Genomic_DNA.
DR   EMBL; AE017042; AAS62213.1; -; Genomic_DNA.
DR   PIR; AI0267; AI0267.
DR   RefSeq; WP_002210639.1; NZ_WUCL01000001.1.
DR   RefSeq; YP_002347170.1; NC_003143.1.
DR   AlphaFoldDB; Q8ZEH4; -.
DR   STRING; 214092.YPO2199; -.
DR   PaxDb; Q8ZEH4; -.
DR   DNASU; 1146989; -.
DR   EnsemblBacteria; AAM85607; AAM85607; y2042.
DR   EnsemblBacteria; AAS62213; AAS62213; YP_1997.
DR   GeneID; 66841445; -.
DR   KEGG; ype:YPO2199; -.
DR   KEGG; ypk:y2042; -.
DR   KEGG; ypm:YP_1997; -.
DR   PATRIC; fig|214092.21.peg.2595; -.
DR   eggNOG; ENOG502Z96Y; Bacteria.
DR   HOGENOM; CLU_073287_0_0_6; -.
DR   OMA; FFRNQFV; -.
DR   Proteomes; UP000000815; Chromosome.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01067; UPF0259; 1.
DR   InterPro; IPR009627; UPF0259.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..256
FT                   /note="UPF0259 membrane protein YPO2199/y2042/YP_1997"
FT                   /id="PRO_0000206522"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01067"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01067"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01067"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01067"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01067"
FT   TRANSMEM        221..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01067"
SQ   SEQUENCE   256 AA;  27754 MW;  B62111D79732A1BB CRC64;
     MPITANTLYR DSFNFLRNQI AAILLLALLT AFITVMLNQT FMPASEQLSI LSIPENDITS
     SGNLSISEIV SQMTPEQQMV LLRVSAVATF SALVGNVLLV GGLLTLIAMV SQGRRVSALQ
     AIGLSLPILP RLLVLMFIST LVIQLGLTFF IVPGVAIAIA LSLSPIIVTN ERMGIFAAMK
     ASAQLAFANV RLIVPAMMLW IAVKLLLLFL ISRFTVLPPT IATIVLSTLS NLASALLLVY
     LFRLYMLLRP VSLDKQ