ID   Y2204_EMENI             Reviewed;         291 AA.
AC   Q5BB76; C8VMJ4;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Uncharacterized protein AN2204;
GN   ORFNames=AN2204;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS   M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA   Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA   Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA   Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA   Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA   Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA   Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA   Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA   Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA   Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA   Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA   Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA   Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA   van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA   Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA   Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA   Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA   Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA   Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA   van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA   Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA   Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT   effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
RN   [3]
RP   INDUCTION, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=17258477; DOI=10.1016/j.fgb.2006.12.001;
RA   Kim Y., Nandakumar M.P., Marten M.R.;
RT   "Proteome map of Aspergillus nidulans during osmoadaptation.";
RL   Fungal Genet. Biol. 44:886-895(2007).
CC   -!- FUNCTION: Involved in osmoadaptation.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- INDUCTION: Down-regulated when grown with elevated levels of potassium
CC       chloride. {ECO:0000269|PubMed:17258477}.
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DR   EMBL; AACD01000035; EAA63861.1; -; Genomic_DNA.
DR   EMBL; BN001307; CBF86377.1; -; Genomic_DNA.
DR   RefSeq; XP_659808.1; XM_654716.1.
DR   AlphaFoldDB; Q5BB76; -.
DR   SMR; Q5BB76; -.
DR   EnsemblFungi; CBF86377; CBF86377; ANIA_02204.
DR   EnsemblFungi; EAA63861; EAA63861; AN2204.2.
DR   GeneID; 2875614; -.
DR   KEGG; ani:AN2204.2; -.
DR   VEuPathDB; FungiDB:AN2204; -.
DR   HOGENOM; CLU_956524_0_0_1; -.
DR   OrthoDB; 1363950at2759; -.
DR   Proteomes; UP000000560; Chromosome VII.
DR   Proteomes; UP000005890; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0071470; P:cellular response to osmotic stress; IEP:AspGD.
PE   1: Evidence at protein level;
KW   Membrane; Reference proteome; Stress response; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..291
FT                   /note="Uncharacterized protein AN2204"
FT                   /id="PRO_0000348282"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   291 AA;  33198 MW;  1A2078A182524300 CRC64;
     MSHLNGSEPS RAQRETEGRW EEKNVLCDQI KEIIAALNDI RTQLAEQNKY LDVLTETYVR
     KPAPTHLVFA QELETGGWEE GSDWGEYADF AQGEILPAPG LEYEGSCEQN YEGKYKGDYE
     ENYEENYEEN YGEENYEEVK GRYREEEKES PKVDSFHVNE TAASRNQREP ILAESKGDMQ
     KQKCYSLEST GPSFYLPLGL VISAHVSQAS FTTVFIILSL AAYIFATFTL WFLREEDWVK
     RIIGSWRLAK ANASASANSN ANAITDSIQA DQDRGSRIPD LLRRRQVLET S