ID   Y2205_MYCTU             Reviewed;         381 AA.
AC   P9WMT7; L0TBL7; P64288; Q10394;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-2015, sequence version 2.
DT   03-AUG-2022, entry version 38.
DE   RecName: Full=Uncharacterized protein Rv2205c;
GN   OrderedLocusNames=Rv2205c; ORFNames=MTCY190.16c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- SIMILARITY: Belongs to the glycerate kinase type-1 family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CCP44982.1; Type=Erroneous initiation; Note=Truncated N-terminus.;
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DR   EMBL; AL123456; CCP44982.1; ALT_INIT; Genomic_DNA.
DR   PIR; F70785; F70785.
DR   RefSeq; NP_216721.2; NC_000962.3.
DR   AlphaFoldDB; P9WMT7; -.
DR   SMR; P9WMT7; -.
DR   STRING; 83332.Rv2205c; -.
DR   PaxDb; P9WMT7; -.
DR   DNASU; 887277; -.
DR   GeneID; 887277; -.
DR   KEGG; mtu:Rv2205c; -.
DR   PATRIC; fig|83332.12.peg.2457; -.
DR   TubercuList; Rv2205c; -.
DR   eggNOG; COG1929; Bacteria.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0009274; C:peptidoglycan-based cell wall; HDA:MTBBASE.
DR   GO; GO:0008887; F:glycerate kinase activity; IEA:InterPro.
DR   GO; GO:0031388; P:organic acid phosphorylation; IEA:InterPro.
DR   Gene3D; 3.40.50.10350; -; 1.
DR   Gene3D; 3.90.1510.10; -; 1.
DR   InterPro; IPR018193; Glyc_kinase_flavodox-like_fold.
DR   InterPro; IPR004381; Glycerate_kinase.
DR   InterPro; IPR018197; Glycerate_kinase_RE-like.
DR   InterPro; IPR036129; Glycerate_kinase_sf.
DR   PANTHER; PTHR21599; PTHR21599; 2.
DR   Pfam; PF02595; Gly_kinase; 2.
DR   PIRSF; PIRSF006078; GlxK; 1.
DR   SUPFAM; SSF110738; SSF110738; 1.
PE   1: Evidence at protein level;
KW   Kinase; Reference proteome; Transferase.
FT   CHAIN           1..381
FT                   /note="Uncharacterized protein Rv2205c"
FT                   /id="PRO_0000071539"
SQ   SEQUENCE   381 AA;  37832 MW;  89CCFFB51AC4B090 CRC64;
     MKGSQASDDA TGSLGPGRLQ LPAMRVLVAP DCYGDSLSAV EAAAAIATGW TRSRPGDSFI
     VAPQSDGGPG FVEVLGSRLG ETRRLRVCGP LNTVVNAAWV FDPGSATAYL ECAQACGLGL
     LGGPPTPETA LAAHSKGVGQ LIAAALRAGA ARIVVGLGGS ACTDGGKGMI AELGGLDAAR
     RQLADVEVIA ASDVEYPLLG PWGTARVFAP QKGADMATVA VLEGRLAAWA IELDAAAGRG
     VSAEPGAGAA GGIGAGLLAV GGRYQSGAAI IAEHTHFADD LADAELIVTG EGRFDEQSLH
     GKVVGAIAAA ARPLAIPVIV LAGQVSLDKS ALRSAGIMAA LSIAEYAGSV RLALADAANQ
     LMGLASQVAA RLGNSGPSGY R