Y2206_MYCTU
ID Y2206_MYCTU Reviewed; 236 AA.
AC P9WLI5; L0TAH7; P64951; Q10395;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 31.
DE RecName: Full=Uncharacterized protein Rv2206;
GN OrderedLocusNames=Rv2206; ORFNames=MTCY190.17;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AL123456; CCP44983.1; -; Genomic_DNA.
DR PIR; G70785; G70785.
DR RefSeq; NP_216722.2; NC_000962.3.
DR RefSeq; WP_003411425.1; NZ_NVQJ01000008.1.
DR AlphaFoldDB; P9WLI5; -.
DR STRING; 83332.Rv2206; -.
DR PaxDb; P9WLI5; -.
DR DNASU; 888107; -.
DR GeneID; 45426182; -.
DR GeneID; 888107; -.
DR KEGG; mtu:Rv2206; -.
DR TubercuList; Rv2206; -.
DR eggNOG; ENOG5031D67; Bacteria.
DR OMA; LMRTLQM; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042783; P:evasion of host immune response; IMP:MTBBASE.
DR InterPro; IPR021403; DUF3043.
DR Pfam; PF11241; DUF3043; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..236
FT /note="Uncharacterized protein Rv2206"
FT /id="PRO_0000103974"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 166..186
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..27
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..108
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 236 AA; 26216 MW; 64A9ED4736A4C346 CRC64;
MKLLGHRKSH GHQRADASPD AGSKDGCRPD SGRTSGSDTS RGSQTTGPKG RPTPKRNQSR
RHTKKGPVAP APMTAAQARA RRKSLAGPKL SREERRAEKA ANRARMTERR ERMMAGEEAY
LLPRDRGPVR RYVRDVVDSR RNLLGLFMPS ALTLLFVMFA VPQVQFYLSP AMLILLALMT
IDAIILGRKV GRLVDTKFPS NTESRWRLGL YAAGRASQIR RLRAPRPQVE RGGDVG
