ID   Y2209_MYCTU             Reviewed;         512 AA.
AC   P9WLI3; L0TBT9; P64953; Q10398;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Uncharacterized protein Rv2209;
GN   OrderedLocusNames=Rv2209; ORFNames=MTCY190.20;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AL123456; CCP44986.1; -; Genomic_DNA.
DR   PIR; B70786; B70786.
DR   RefSeq; NP_216725.1; NC_000962.3.
DR   RefSeq; WP_003899218.1; NZ_NVQJ01000008.1.
DR   AlphaFoldDB; P9WLI3; -.
DR   SMR; P9WLI3; -.
DR   STRING; 83332.Rv2209; -.
DR   PaxDb; P9WLI3; -.
DR   DNASU; 887230; -.
DR   GeneID; 887230; -.
DR   KEGG; mtu:Rv2209; -.
DR   TubercuList; Rv2209; -.
DR   eggNOG; COG2814; Bacteria.
DR   OMA; FGVRGML; -.
DR   PhylomeDB; P9WLI3; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..512
FT                   /note="Uncharacterized protein Rv2209"
FT                   /id="PRO_0000103977"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        55..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        123..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        238..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        263..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        294..314
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        329..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        359..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        386..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          428..512
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        440..459
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   512 AA;  53579 MW;  6C6282A4546F9639 CRC64;
     MPASRLVRQV SAPRNLFGRL VAQGGFYTAG LQLGSGAVVL PVICAHQGLT WAAGLLYPAF
     CIGAILGNSL SPLILQRAGQ LRHLLMAAIS ATAAALVVCN AAVPWTGVGV AAVFLATTGA
     GGVVTGVSSV AYTDMISSML PAVRRGELLL TQGAAGSVLA TGVTLVIVPM LAHGNEMARY
     HDLLWLGAAG LVCSGIAALF VGPMRSVSVT TATRMPLREI YWMGFAIARS QPWFRRYMTT
     YLLFVPISLG TTFFSLRAAQ SNGSLHVLVI LSSIGLVVGS MLWRQINRLF GVRGLLLGSA
     LLNAAAALLC MVAESCGQWV HAWAYGTAFL LATVAAQTVV AASISWISVL APERYRATLI
     CVGSTLAAVE ATVLGVALGG IAQKHATIWP VVVVLTLAVI AAVASLRAPT RIGVTADTSP
     QAATLQAYRP ATPNPIHSDE RSTPPDHLSV RRGQLRHVWD SRRPAPPLNR PSCRRAARRP
     APGKPAAALP QPRHPAVGVR EGAPLDAGQR IA