ID   Y2211_CORGL             Reviewed;         539 AA.
AC   Q8NNI8; Q6M3M8;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Uncharacterized transporter Cgl2211/cg2425;
GN   OrderedLocusNames=Cgl2211, cg2425;
OS   Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 /
OS   JCM 1318 / LMG 3730 / NCIMB 10025).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=196627;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC   10025;
RX   PubMed=12743753; DOI=10.1007/s00253-003-1328-1;
RA   Ikeda M., Nakagawa S.;
RT   "The Corynebacterium glutamicum genome: features and impacts on
RT   biotechnological processes.";
RL   Appl. Microbiol. Biotechnol. 62:99-109(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC   10025;
RX   PubMed=12948626; DOI=10.1016/s0168-1656(03)00154-8;
RA   Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A.,
RA   Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A.,
RA   Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F.,
RA   Moeckel B., Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O.,
RA   Sahm H., Wendisch V.F., Wiegraebe I., Tauch A.;
RT   "The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its
RT   impact on the production of L-aspartate-derived amino acids and vitamins.";
RL   J. Biotechnol. 104:5-25(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC       {ECO:0000305}.
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DR   EMBL; BA000036; BAB99604.1; -; Genomic_DNA.
DR   EMBL; BX927154; CAF20551.1; -; Genomic_DNA.
DR   RefSeq; NP_601414.1; NC_003450.3.
DR   RefSeq; WP_003859640.1; NC_006958.1.
DR   AlphaFoldDB; Q8NNI8; -.
DR   SMR; Q8NNI8; -.
DR   STRING; 196627.cg2425; -.
DR   TCDB; 2.A.81.1.3; the aspartate:alanine exchanger (aaex) family.
DR   KEGG; cgb:cg2425; -.
DR   KEGG; cgl:Cgl2211; -.
DR   PATRIC; fig|196627.13.peg.2147; -.
DR   eggNOG; COG0569; Bacteria.
DR   eggNOG; COG2985; Bacteria.
DR   HOGENOM; CLU_035023_3_0_11; -.
DR   OMA; RDGKNYF; -.
DR   Proteomes; UP000000582; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; -; 1.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR006512; YidE_YbjL.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   Pfam; PF02080; TrkA_C; 1.
DR   SUPFAM; SSF116726; SSF116726; 2.
DR   TIGRFAMs; TIGR01625; YidE_YbjL_dupl; 2.
DR   PROSITE; PS51202; RCK_C; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..539
FT                   /note="Uncharacterized transporter Cgl2211/cg2425"
FT                   /id="PRO_0000208769"
FT   TRANSMEM        4..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        27..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        56..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        155..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        360..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        422..444
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        453..475
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        516..538
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          187..269
FT                   /note="RCK C-terminal 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
FT   DOMAIN          271..352
FT                   /note="RCK C-terminal 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
SQ   SEQUENCE   539 AA;  57150 MW;  EE6E907F6D29FD7B CRC64;
     MSFLVENQLL ALVVIMTVGL LLGRIKIFGF RLGVAAVLFV GLALSTIEPD ISVPSLIYVV
     GLSLFVYTIG LEAGPGFFTS MKTTGLRNNA LTLGAIIATT ALAWALITVL NIDAASGAGM
     LTGALTNTPA MAAVVDALPS LIDDTGQLHL IAELPVVAYS LAYPLGVLIV ILSIAIFSSV
     FKVDHNKEAE EAGVAVQELK GRRIRVTVAD LPALENIPEL LNLHVIVSRV ERDGEQFIPL
     YGEHARIGDV LTVVGADEEL NRAEKAIGEL IDGDPYSNVE LDYRRIFVSN TAVVGTPLSK
     LQPLFKDMLI TRIRRGDTDL VASSDMTLQL GDRVRVVAPA EKLREATQLL GDSYKKLSDF
     NLLPLAAGLM IGVLVGMVEF PLPGGSSLKL GNAGGPLVVA LLLGMINRTG KFVWQIPYGA
     NLALRQLGIT LFLAAIGTSA GAGFRSAISD PQSLTIIGFG ALLTLFISIT VLFVGHKLMK
     IPFGETAGIL AGTQTHPAVL SYVSDASRNE LPAMGYTSVY PLAMIAKILA AQTLLFLLI