ID   Y2216_MYCTO             Reviewed;         301 AA.
AC   P9WGP6; L0TAI8; P67232; Q10403;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 35.
DE   RecName: Full=Epimerase family protein MT2273;
GN   OrderedLocusNames=MT2273;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. SDR39U1 subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK46558.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE000516; AAK46558.1; ALT_INIT; Genomic_DNA.
DR   PIR; A70787; A70787.
DR   RefSeq; WP_003411454.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WGP6; -.
DR   SMR; P9WGP6; -.
DR   EnsemblBacteria; AAK46558; AAK46558; MT2273.
DR   GeneID; 45426192; -.
DR   KEGG; mtc:MT2273; -.
DR   PATRIC; fig|83331.31.peg.2447; -.
DR   HOGENOM; CLU_047373_0_2_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   InterPro; IPR013549; DUF1731.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR010099; SDR39U1.
DR   Pfam; PF08338; DUF1731; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR01777; yfcH; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..301
FT                   /note="Epimerase family protein MT2273"
FT                   /id="PRO_0000428325"
SQ   SEQUENCE   301 AA;  31672 MW;  26CD511BE6A437FE CRC64;
     MANAVVAIAG SSGLIGSALT AALRAADHTV LRIVRRAPAN SEELHWNPES GEFDPHALTD
     VDAVVNLCGV NIAQRRWSGA FKQSLRDSRI TPTEVLSAAV ADAGVATLIN ASAVGYYGNT
     KDRVVDENDS AGTGFLAQLC VDWETATRPA QQSGARVVLA RTGVVLSPAG GMLRRMRPLF
     SVGLGARLGS GRQYMSWISL EDEVRALQFA IAQPNLSGPV NLTGPAPVTN AEFTTAFGRA
     VNRPTPLMLP SVAVRAAFGE FADEGLLIGQ RAIPSALERA GFQFHHNTIG EALGYATTRP
     G