ID   Y2219_MYCTO             Reviewed;         250 AA.
AC   P9WLI0; L0TBU9; Q10405;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Uncharacterized protein MT2276;
DE   Flags: Precursor;
GN   OrderedLocusNames=MT2276;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000516; AAK46561.1; -; Genomic_DNA.
DR   PIR; D70787; D70787.
DR   RefSeq; WP_003411463.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WLI0; -.
DR   EnsemblBacteria; AAK46561; AAK46561; MT2276.
DR   GeneID; 45426195; -.
DR   KEGG; mtc:MT2276; -.
DR   PATRIC; fig|83331.31.peg.2450; -.
DR   HOGENOM; CLU_089257_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR025445; DUF4191.
DR   Pfam; PF13829; DUF4191; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..250
FT                   /note="Uncharacterized protein MT2276"
FT                   /id="PRO_0000427475"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          226..250
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   250 AA;  26864 MW;  ADC433144243095C CRC64;
     MAKPRNAAES KAAKAQANAA RKAAARQRRA QLWQAFTLQR KEDKRLLPYM IGAFLLIVGA
     SVGVGVWAGG FTMFTMIPLG VLLGALVAFV IFGRRAQRTV YRKAEGQTGA AAWALDNLRG
     KWRVTPGVAA TGNLDAVHRV IGRPGVIFVG EGSAARVKPL LAQEKKRTAR LVGDVPIYDI
     IVGNGDGEVP LAKLERHLTR LPANITVKQM DTVESRLAAL GSRAGAGVMP KGPLPTTAKM
     RSVQRTVRRK