ID   Y221_AFV1Y              Reviewed;         221 AA.
AC   Q70LC9;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   29-SEP-2021, entry version 42.
DE   RecName: Full=Uncharacterized protein ORF221;
GN   ORFNames=ORF221;
OS   Acidianus filamentous virus 1 (isolate United States/Yellowstone) (AFV-1).
OC   Viruses; Adnaviria; Zilligvirae; Taleaviricota; Tokiviricetes;
OC   Ligamenvirales; Lipothrixviridae; Gammalipothrixvirus.
OX   NCBI_TaxID=654909;
OH   NCBI_TaxID=563177; Acidianus hospitalis.
OH   NCBI_TaxID=12915; Acidianus infernus.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=14592760; DOI=10.1016/s0042-6822(03)00481-1;
RA   Bettstetter M., Peng X., Garrett R.A., Prangishvili D.;
RT   "AFV1, a novel virus infecting hyperthermophilic archaea of the genus
RT   acidianus.";
RL   Virology 315:68-79(2003).
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ567472; CAD98951.1; -; Genomic_DNA.
DR   RefSeq; YP_003747.1; NC_005830.1.
DR   SMR; Q70LC9; -.
DR   PRIDE; Q70LC9; -.
DR   GeneID; 2769186; -.
DR   KEGG; vg:2769186; -.
DR   Proteomes; UP000000514; Genome.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Host membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..221
FT                   /note="Uncharacterized protein ORF221"
FT                   /id="PRO_0000384566"
FT   TOPO_DOM        1..45
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        67..221
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   221 AA;  25250 MW;  858A685E9FB089FC CRC64;
     MYAPIRSPIT ELNESTPSSI PVATSYATCS ASFAKLVALL VDDMAGLSIV LSEIYIYFKL
     LFLIVITESI QNKLEDIVKE YKKRGIDLGI ITNVDEVSLF FDTSQYAEAI KKKVIEIVRQ
     SGTGRAKIDF KTNGYVIKFA IQRGYYNRNT IEKLKSLVDY LHEQKIRCGY EIKGDLIFVM
     SLTDFLQKIS EDVKEKLKDE RVKIASKQEY TKYIVVIKVE Q