ID   Y2224_LISMO             Reviewed;         377 AA.
AC   Q8Y552;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=UPF0754 membrane protein lmo2224;
GN   OrderedLocusNames=lmo2224;
OS   Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=169963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-679 / EGD-e;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0754 family. {ECO:0000305}.
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DR   EMBL; AL591982; CAD00302.1; -; Genomic_DNA.
DR   PIR; AH1352; AH1352.
DR   RefSeq; NP_465748.1; NC_003210.1.
DR   RefSeq; WP_009930567.1; NZ_CP023861.1.
DR   AlphaFoldDB; Q8Y552; -.
DR   STRING; 169963.lmo2224; -.
DR   PaxDb; Q8Y552; -.
DR   EnsemblBacteria; CAD00302; CAD00302; CAD00302.
DR   GeneID; 985253; -.
DR   KEGG; lmo:lmo2224; -.
DR   PATRIC; fig|169963.11.peg.2276; -.
DR   eggNOG; COG4399; Bacteria.
DR   HOGENOM; CLU_042384_0_0_9; -.
DR   OMA; DTIMGSL; -.
DR   PhylomeDB; Q8Y552; -.
DR   BioCyc; LMON169963:LMO2224-MON; -.
DR   Proteomes; UP000000817; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007383; DUF445.
DR   InterPro; IPR016991; UCP032178.
DR   Pfam; PF04286; DUF445; 1.
DR   PIRSF; PIRSF032178; UCP032178; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..377
FT                   /note="UPF0754 membrane protein lmo2224"
FT                   /id="PRO_0000388296"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        357..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   377 AA;  43188 MW;  F76A1FE9BD1CF3C9 CRC64;
     MSVLFTILLM AVIGGFIGAM TNYIAIRMLF RPYKAIYLFN KRLPFTPGLI PKRRDELAEH
     IGKVVVSHLL TEDAIRARLL DENLQKEITD TITKMFHEKM KLETTPNELL HHFGYENAEI
     RSMAWIEKTL EKEINHFLST KKTTKMSDLI PTMLESELTT KLPHVTERIT SKMTLFVASE
     EGKIQIKQML QKFFEEHGKM GSMARMFINI DSFSEKIQQE GLKLIGQEDT KNLINQLLTT
     EWKNFEAKEL QELIPTEKQA HLAGQLTSEL IQTLPHEKLF NQPIQVILRG YEAAITEKVI
     PFAVERMLDF VATHSAEIVE RMDLAKLVET QIATFSLPEI EKLVVEISGR ELKMITYLGG
     ILGGFIGIIQ GILAMWI