ID   Y2225_SALRD             Reviewed;         952 AA.
AC   Q2S0F1;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=UPF0182 protein SRU_2225 {ECO:0000255|HAMAP-Rule:MF_01600};
GN   OrderedLocusNames=SRU_2225;
OS   Salinibacter ruber (strain DSM 13855 / M31).
OC   Bacteria; Bacteroidetes; Bacteroidetes Order II. Incertae sedis;
OC   Rhodothermaceae; Salinibacter.
OX   NCBI_TaxID=309807;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13855 / CECT 5946 / M31;
RX   PubMed=16330755; DOI=10.1073/pnas.0509073102;
RA   Mongodin E.F., Nelson K.E., Daugherty S., DeBoy R.T., Wister J., Khouri H.,
RA   Weidman J., Walsh D.A., Papke R.T., Sanchez Perez G., Sharma A.K.,
RA   Nesbo C.L., MacLeod D., Bapteste E., Doolittle W.F., Charlebois R.L.,
RA   Legault B., Rodriguez-Valera F.;
RT   "The genome of Salinibacter ruber: convergence and gene exchange among
RT   hyperhalophilic bacteria and archaea.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:18147-18152(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01600};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01600}.
CC   -!- SIMILARITY: Belongs to the UPF0182 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01600}.
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DR   EMBL; CP000159; ABC44761.1; -; Genomic_DNA.
DR   RefSeq; WP_011404951.1; NC_007677.1.
DR   RefSeq; YP_446330.1; NC_007677.1.
DR   AlphaFoldDB; Q2S0F1; -.
DR   SMR; Q2S0F1; -.
DR   EnsemblBacteria; ABC44761; ABC44761; SRU_2225.
DR   KEGG; sru:SRU_2225; -.
DR   PATRIC; fig|309807.25.peg.2318; -.
DR   eggNOG; COG1615; Bacteria.
DR   HOGENOM; CLU_007733_0_0_10; -.
DR   OMA; HLRYPQD; -.
DR   Proteomes; UP000008674; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01600; UPF0182; 1.
DR   InterPro; IPR005372; UPF0182.
DR   PANTHER; PTHR39344; PTHR39344; 1.
DR   Pfam; PF03699; UPF0182; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..952
FT                   /note="UPF0182 protein SRU_2225"
FT                   /id="PRO_0000291294"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        168..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        207..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        277..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   REGION          917..952
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        926..952
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   952 AA;  107282 MW;  80CDF99F515EB808 CRC64;
     MSILRSSRLL QILLGIIGVV FTVLLVTPGL VVEYFWLSEL DYSSVFWTIR GAQVLLFVLV
     FLVAGLYFGG NFRVLIGNIP PLWASRWAQE GEAPEVGGEP LTRDRLQRLG YVVAGVLSLL
     FAAGFSGRWN DLLRFWYAGS YGQADPVYGV DLAFYMLELP FLQSLQSAVV GLAFLGLLAL
     VTGYVIAGQI GIQDGGFEAD SGALRHLGAN LIFLLLGWAW GFYLDLYELL QEGGGAVYGA
     GYTDVNVVIP ALYVMVAATL VLAGLVGLNL YRRRLRLLGI GGAGYLVLLV GGLVLAPSLV
     TQLTVLPSEL QVERPYLENN IDMTREAYAL GDFKERSYPA QPDLPADAVE QNEETIDNVR
     LWDPRLLIDT YRQLQEIRLY YEFYSVDVDR YMLDGDYRQV MVSPRELTQQ LPEDTWDNRH
     VRFTHGYGSV SNLVAREGSE GSPEFLTQDI PPQSKYESLD VDNPALYYGE RTPTYRIVPA
     GVPGDSLELD YPRSGENKYT RYGGEGGVSV GSFWKQLLFS YYMGDFNILL TDYIQDDSQI
     QFWNQVEERV RHVAPFLKLD KDPYLVHGDD RHYYIADAYT TSNSFPYSEP IRGQQGYQGT
     RYIRNSVKVV VDAYNGDVSL YVSNPEDPII QTYQRIFPDL FQPLDAMPEL LQNHIRYPQD
     FFEIQMERYR RYHQTQPQVF YNNEDLWTRP QEQYANQQRK MEPYYILTDL PGKDDAGLEF
     MLMLPMTPDG RDNMIGWVAA RSDPPNYGEV VVYELPKDRL IRGPNQIESR IDQDTEISQQ
     LSLWDQRGSS VIRGNLIVVP IEESFLYVEP IYLIADEIQI PEMQRVIAAT DQDVAMKRTL
     RQSLNSVLGE QVVETRDQAL AQMQQAAQTA QAASPEQVEG LERAKELIQE ARDALQGGDF
     ATFGDRFDEL QQVLNDVPLP DTTGTVPPPT SSDTTGTMTA PTGDVSEVTG GS