ID   Y2226_MYCTU             Reviewed;         513 AA.
AC   P9WLH9; L0T8Z9; Q10510;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Uncharacterized protein Rv2226;
GN   OrderedLocusNames=Rv2226; ORFNames=MTCY427.07;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
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DR   EMBL; AL123456; CCP45004.1; -; Genomic_DNA.
DR   PIR; F70776; F70776.
DR   RefSeq; NP_216742.1; NC_000962.3.
DR   RefSeq; WP_003911786.1; NZ_NVQJ01000008.1.
DR   AlphaFoldDB; P9WLH9; -.
DR   SMR; P9WLH9; -.
DR   STRING; 83332.Rv2226; -.
DR   PaxDb; P9WLH9; -.
DR   PRIDE; P9WLH9; -.
DR   DNASU; 888513; -.
DR   GeneID; 888513; -.
DR   KEGG; mtu:Rv2226; -.
DR   TubercuList; Rv2226; -.
DR   eggNOG; COG3025; Bacteria.
DR   eggNOG; COG5607; Bacteria.
DR   OMA; GSDAGWH; -.
DR   PhylomeDB; P9WLH9; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005829; C:cytosol; HDA:MTBBASE.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   Gene3D; 1.40.20.10; -; 1.
DR   InterPro; IPR007899; CHAD_dom.
DR   InterPro; IPR038186; CHAD_dom_sf.
DR   InterPro; IPR033469; CYTH-like_dom_sf.
DR   InterPro; IPR023577; CYTH_domain.
DR   Pfam; PF05235; CHAD; 1.
DR   Pfam; PF01928; CYTH; 1.
DR   SMART; SM00880; CHAD; 1.
DR   SMART; SM01118; CYTH; 1.
DR   SUPFAM; SSF55154; SSF55154; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..513
FT                   /note="Uncharacterized protein Rv2226"
FT                   /id="PRO_0000103979"
SQ   SEQUENCE   513 AA;  56333 MW;  8E74BDA8945D7B99 CRC64;
     MPVEAPRPAR HLEVERKFDV IESTVSPSFE GIAAVVRVEQ SPTQQLDAVY FDTPSHDLAR
     NQITLRRRTG GADAGWHLKL PAGPDKRTEM RAPLSASGDA VPAELLDVVL AIVRDQPVQP
     VARISTHRES QILYGAGGDA LAEFCNDDVT AWSAGAFHAA GAADNGPAEQ QWREWELELV
     TTDGTADTKL LDRLANRLLD AGAAPAGHGS KLARVLGATS PGELPNGPQP PADPVHRAVS
     EQVEQLLLWD RAVRADAYDA VHQMRVTTRK IRSLLTDSQE SFGLKESAWV IDELRELADV
     LGVARDAEVL GDRYQRELDA LAPELVRGRV RERLVDGARR RYQTGLRRSL IALRSQRYFR
     LLDALDALVS ERAHATSGEE SAPVTIDAAY RRVRKAAKAA KTAGDQAGDH HRDEALHLIR
     KRAKRLRYTA AATGADNVSQ EAKVIQTLLG DHQDSVVSRE HLIQQAIAAN TAGEDTFTYG
     LLYQQEADLA ERCREQLEAA LRKLDKAVRK ARD